Melatonin modulates Nrf2 activity to protect porcine pre‐pubertal Sertoli cells from the abnormal H2O2 generation and reductive stress effects of cadmium

Melatonin (MLT) is a cytoprotective agent holding potential to prevent cadmium (Cd) toxicity and its impact in testicular function and fertility. In this study, we explored such potential in porcine pre‐pubertal Sertoli cells (SCs). Cd toxicity resulted in impaired SC viability and function, abnorma...

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Veröffentlicht in:	Journal of pineal research 2022-08, Vol.73 (1), p.n/a
Hauptverfasser:	Bartolini, Desirée, Arato, Iva, Mancuso, Francesca, Giustarini, Daniela, Bellucci, Catia, Vacca, Carmine, Aglietti, Maria Chiara, Stabile, Anna Maria, Rossi, Ranieri, Cruciani, Gabriele, Rende, Mario, Calafiore, Riccardo, Luca, Giovanni, Galli, Francesco
Format:	Artikel
Sprache:	eng
Schlagworte:	cadmium glutathione melatonin NFkB Nrf2 reductive stress Sertoli cells
Online-Zugang:	Volltext
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