Down‐regulation of circDMNT3B is conducive to intestinal mucosal permeability dysfunction of rats with sepsis via sponging miR‐20b‐5p

Sepsis is a life‐threatening syndrome with a high risk of mortality, which is caused by the dysregulated host response to infection. We examined significant roles of circDMNT3B and miR‐20b‐5p in the intestinal mucosal permeability dysfunction of rats with sepsis. SD rats were randomly divided into 6...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cellular and molecular medicine 2020-06, Vol.24 (12), p.6731-6740
Hauptverfasser:	Liu, Jiao, Liu, Yongan, Zhang, Lidi, Chen, Yizhu, Du, Hangxiang, Wen, Zhenliang, Wang, Tao, Chen, Dechang
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen Animals Apoptosis Apoptosis - genetics Base Sequence Bioengineering Biomarkers Caco-2 Cells Cell growth Cell Proliferation - genetics Cell survival Cell Survival - genetics Chromosome 5 circDMNT3B Down-Regulation - genetics Enzyme-linked immunosorbent assay Flow cytometry Gene expression Gene Silencing Humans Inflammation Inflammation - genetics Inflammation - pathology Intestinal Mucosa - pathology Intestinal Mucosa - physiopathology intestinal permeability Intestine Laboratory animals Lactic acid Lipopolysaccharides Male Malondialdehyde Manufacturers Medical diagnosis Medical prognosis Membrane permeability MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism miR‐20b‐5p Mucosa Original Oxidative Stress - genetics Permeability Rats, Sprague-Dawley RNA, Circular - genetics RNA, Circular - metabolism Sepsis Sepsis - genetics Sepsis - physiopathology Superoxide dismutase
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!