Deorphaning a solute carrier 22 family member, SLC22A15, through functional genomic studies

The human solute carrier 22A (SLC22A) family consists of 23 members, representing one of the largest families in the human SLC superfamily. Despite their pharmacological and physiological importance in the absorption and disposition of a range of solutes, eight SLC22A family members remain classifie...

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Veröffentlicht in:	The FASEB journal 2020-12, Vol.34 (12), p.15734-15752
Hauptverfasser:	Yee, Sook Wah, Buitrago, Dina, Stecula, Adrian, Ngo, Huy X., Chien, Huan‐Chieh, Zou, Ling, Koleske, Megan L., Giacomini, Kathleen M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry & Molecular Biology Biological Transport - drug effects Biological Transport - genetics Biology carnitine Carnitine - pharmacology carnosine Carnosine - pharmacology Cell Biology Cell Line ergothioneine Ergothioneine - pharmacology Gabapentin - pharmacology Genomics - methods HEK293 Cells Humans Life Sciences & Biomedicine Life Sciences & Biomedicine - Other Topics Ligands metabolomic Organic Cation Transport Proteins - genetics Phylogeny Science & Technology Transfection - methods transporter
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