Identification of the b, d, and e analogs of vitamin B12 as monocarboxylic acids by 15N NMR spectroscopy

Identification of the b, d, and e analogs of vitamin B12 as monocarboxylic acids by 15N NMR spectroscopy

15N NMR spectra of b−, d−, and e‐cyanocobalamin (vitamin B12) and the products of their amidation with 15N‐labeled ammonia show that these analogs are monocarboxylic acids of vitamin B12 which result from hydrolysis at the respective propionamide groups.

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Veröffentlicht in:Magnetic resonance in chemistry 1989-02, Vol.27 (2), p.127-129
Hauptverfasser: Difeo, Thomas J., Schiksnis, Robert A., Kohli, Rakesh K., Opella, Stanley J., Nath, Amar
Format: Artikel
Sprache:eng
Schlagworte:
15N NMR
Vitamin B12
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Zusammenfassung:15N NMR spectra of b−, d−, and e‐cyanocobalamin (vitamin B12) and the products of their amidation with 15N‐labeled ammonia show that these analogs are monocarboxylic acids of vitamin B12 which result from hydrolysis at the respective propionamide groups.
ISSN:0749-1581
1097-458X
DOI:10.1002/mrc.1260270206