Transforming growth factor β regulation of cell proliferation

Two types of transforming growth factors (TGF) have been purified and well characterized, TGFα and TGFβ. TGFα is a 5.6 kD single chain molecule that shows sequence homology to epidermal growth factor (EGF), binds to the EGF receptor, and has biological effects very similar to those of EGF. TGFβ is d...

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Veröffentlicht in:	Journal of cellular physiology 1987, Vol.133 (S5), p.1-7
Hauptverfasser:	Moses, Harold L., Coffey Jr, Robert J., Leof, Edward B., Lyons, Russette M., Keski-Oja, Jorma
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Division - drug effects Cell Transformation, Neoplastic - drug effects Cells, Cultured Epithelial Cells Epithelium - drug effects Fibroblasts - drug effects Growth Substances - isolation & purification Growth Substances - pharmacology Humans Peptides - isolation & purification Peptides - pharmacology Terminology as Topic Transforming Growth Factors Tumor Cells, Cultured
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