The Stereoselective Total Synthesis of (6S)-5,6-Dihydro-6-[(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one via Prins Cyclization
The stereoselective total synthesis of an antiproliferative and antifungal α‐pyrone natural product (6S)‐5,6‐dihydro‐6‐[(2R)‐2‐hydroxy‐6‐phenylhexyl]‐2H‐pyran‐2‐one is described. The key steps involved are the Prins cyclization, Mitsunobu reaction, and ring‐closing metathesis reaction....
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| Veröffentlicht in: | Helvetica chimica acta 2010-07, Vol.93 (7), p.1432-1438 |
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| container_title | Helvetica chimica acta |
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| creator | Yadav, Jhillu Singh Chandrakanth, Dandekar Rao, Yerragorla Gopala Ravindar, Kontham Reddy, Basi V. Subba |
| description | The stereoselective total synthesis of an antiproliferative and antifungal α‐pyrone natural product (6S)‐5,6‐dihydro‐6‐[(2R)‐2‐hydroxy‐6‐phenylhexyl]‐2H‐pyran‐2‐one is described. The key steps involved are the Prins cyclization, Mitsunobu reaction, and ring‐closing metathesis reaction. |
| doi_str_mv | 10.1002/hlca.200900414 |
| format | Article |
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| ispartof | Helvetica chimica acta, 2010-07, Vol.93 (7), p.1432-1438 |
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| language | eng |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | 2H-Pyran-2-ones Mitsunobu reaction Prins cyclization Ring-closing metathesis (RCM) |
| title | The Stereoselective Total Synthesis of (6S)-5,6-Dihydro-6-[(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one via Prins Cyclization |
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