TiO2 as a Reusable Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones under Solvent-Free Conditions

An efficient solvent‐free method for the synthesis of various 3,4‐dihydropyrimidin‐2(1H)‐ones using TiO2 as a recyclable heterogeneous catalyst is described. Compared to known methods, satisfactory results are obtained with excellent yields, short reaction times, and simplicity in the experimental p...

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Veröffentlicht in:Helvetica chimica acta 2010-02, Vol.93 (2), p.261-264
Hauptverfasser: Kassaee, Mohammad Zaman, Masrouri, Hassan, Movahedi, Farnaz, Mohammadi, Reza
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creator Kassaee, Mohammad Zaman
Masrouri, Hassan
Movahedi, Farnaz
Mohammadi, Reza
description An efficient solvent‐free method for the synthesis of various 3,4‐dihydropyrimidin‐2(1H)‐ones using TiO2 as a recyclable heterogeneous catalyst is described. Compared to known methods, satisfactory results are obtained with excellent yields, short reaction times, and simplicity in the experimental procedure.
doi_str_mv 10.1002/hlca.200900197
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subjects 4-dihydro
Biginelli reaction
Catalysis
Multicomponent reactions
Pyrimidin-2(1H)-ones
Pyrimidin‐2(1H)‐ones, 3,4‐dihydro
Solvent-free chemistry
title TiO2 as a Reusable Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones under Solvent-Free Conditions
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