Full title: A large‐scale transcriptome‐wide association study (TWAS) of 10 blood cell phenotypes reveals complexities of TWAS fine‐mapping

Hematological measures are important intermediate clinical phenotypes for many acute and chronic diseases and are highly heritable. Although genome‐wide association studies (GWAS) have identified thousands of loci containing trait‐associated variants, the causal genes underlying these associations a...

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Veröffentlicht in:Genetic epidemiology 2022-02, Vol.46 (1), p.3-16
Hauptverfasser: Tapia, Amanda L., Rowland, Bryce T., Rosen, Jonathan D., Preuss, Michael, Young, Kris, Graff, Misa, Choquet, Hélène, Couper, David J., Buyske, Steve, Bien, Stephanie A., Jorgenson, Eric, Kooperberg, Charles, Loos, Ruth J. F., Morrison, Alanna C., North, Kari E., Yu, Bing, Reiner, Alexander P., Li, Yun, Raffield, Laura M.
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Sprache:eng
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