The chemical development of selective and specific serotonin S2-antagonists

Four types of chemical intermediates were prepared to synthesize novel piperidine derivatives inspired by the butyrophenones benperidol and lenperone and by the diphenylbutyl neuroleptic pimozide. The fist type, comprising benzimidazolone alkyl intermediates, yielded declenperone and milenperone and...

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Veröffentlicht in:	Drug development research 1986-05, Vol.8 (1-4), p.133-140
Hauptverfasser:	Kennis, Ludo E. J., Vandenberk, Jan, Boey, Jozef M., Mertens, Jos C., van Heertum, Albert H. M., Janssen, Marcel, Awouters, Frans
Format:	Artikel
Sprache:	eng
Schlagworte:	domperidone dopamine D2-antagonists ketanserin ritanserin
Online-Zugang:	Volltext
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