Head and neck cancer
Tumors of the head and neck comprise an important neoplasia group, the incidence of which is increasing in many parts of the world. Recent advances in diagnostic and therapeutic techniques for these lesions have yielded novel molecular targets, uncovered signal pathway dominance, and advanced early...
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Veröffentlicht in: | Cancer 2010-11, Vol.116 (21), p.4914-4925 |
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creator | Rezende, Taia Maria Berto Freire, Mirna de Souza Franco, Octávio Luiz |
description | Tumors of the head and neck comprise an important neoplasia group, the incidence of which is increasing in many parts of the world. Recent advances in diagnostic and therapeutic techniques for these lesions have yielded novel molecular targets, uncovered signal pathway dominance, and advanced early cancer detection. Proteomics is a powerful tool for investigating the distribution of proteins and small molecules within biological systems through the analysis of different types of samples. The proteomic profiles of different types of cancer have been studied, and this has provided remarkable advances in cancer understanding. This review covers recent advances for head and neck cancer; it encompasses the risk factors, pathogenesis, proteomic tools that can help in understanding cancer, and new proteomic findings in this type of cancer. Cancer 2010. © 2010 American Cancer Society.
This review emphasizes the importance of proteomic tools in understanding head and neck cancer, highlighting proteomic tools used in cancer studies and new findings in head and neck cancer diagnostic and physiological biomarkers. |
doi_str_mv | 10.1002/cncr.25245 |
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This review emphasizes the importance of proteomic tools in understanding head and neck cancer, highlighting proteomic tools used in cancer studies and new findings in head and neck cancer diagnostic and physiological biomarkers.</description><subject>cancer pathogenesis</subject><subject>cancer risk factors</subject><subject>diagnostic biomarkers</subject><subject>head and neck cancer</subject><subject>proteomics</subject><issn>0008-543X</issn><issn>1097-0142</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNotj8FKAzEQhkNR6Fp7ER9gXyB1ZpIxm6MsaoWiIAq9hXQyC9W6yO5B-va21dP__ZcPPmOuEBYIQDfSy7AgJs8TUyHEYAE9nZkKABrL3q2n5mIcPw43ELvKXC81lzr3pe5VPmvJvehwac67vBt1_r8z8_5w_9Yu7erl8am9W1khZraNblA5cg4-h1so6rWTCBoPdmDcFJXigzhUKl3UToGoyRGpcAwugJsZ_PP-bHe6T9_D9isP-4SQjjHpGJNOMal9bl9P5H4BYyw9JA</recordid><startdate>20101101</startdate><enddate>20101101</enddate><creator>Rezende, Taia Maria Berto</creator><creator>Freire, Mirna de Souza</creator><creator>Franco, Octávio Luiz</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope/></search><sort><creationdate>20101101</creationdate><title>Head and neck cancer</title><author>Rezende, Taia Maria Berto ; Freire, Mirna de Souza ; Franco, Octávio Luiz</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2555-8eb1e595a74a760de4efc90e9000051bdecd47c31e2df9efe0228a912d5973703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>cancer pathogenesis</topic><topic>cancer risk factors</topic><topic>diagnostic biomarkers</topic><topic>head and neck cancer</topic><topic>proteomics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rezende, Taia Maria Berto</creatorcontrib><creatorcontrib>Freire, Mirna de Souza</creatorcontrib><creatorcontrib>Franco, Octávio Luiz</creatorcontrib><jtitle>Cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rezende, Taia Maria Berto</au><au>Freire, Mirna de Souza</au><au>Franco, Octávio Luiz</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Head and neck cancer</atitle><jtitle>Cancer</jtitle><date>2010-11-01</date><risdate>2010</risdate><volume>116</volume><issue>21</issue><spage>4914</spage><epage>4925</epage><pages>4914-4925</pages><issn>0008-543X</issn><eissn>1097-0142</eissn><abstract>Tumors of the head and neck comprise an important neoplasia group, the incidence of which is increasing in many parts of the world. Recent advances in diagnostic and therapeutic techniques for these lesions have yielded novel molecular targets, uncovered signal pathway dominance, and advanced early cancer detection. Proteomics is a powerful tool for investigating the distribution of proteins and small molecules within biological systems through the analysis of different types of samples. The proteomic profiles of different types of cancer have been studied, and this has provided remarkable advances in cancer understanding. This review covers recent advances for head and neck cancer; it encompasses the risk factors, pathogenesis, proteomic tools that can help in understanding cancer, and new proteomic findings in this type of cancer. Cancer 2010. © 2010 American Cancer Society.
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subjects | cancer pathogenesis cancer risk factors diagnostic biomarkers head and neck cancer proteomics |
title | Head and neck cancer |
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