Subthalamic Nucleus Stimulation Modulates Motor Epileptic Activity in Humans

Objective Pharmaco‐refractory focal motor epileptic seizures pose a significant challenge. Deep brain stimulation (DBS) is a recently recognized therapeutic option for the treatment of refractory epilepsy. To identify the specific target for focal motor seizures, we evaluate the modulatory effects o...

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Veröffentlicht in:	Annals of neurology 2020-08, Vol.88 (2), p.283-296
Hauptverfasser:	Ren, Liankun, Yu, Tao, Wang, Di, Wang, Xueyuan, Ni, Duanyu, Zhang, Guojun, Bartolomei, Fabrice, Wang, Yuping, Li, Yongjie
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Child Convulsions & seizures Cortex (motor) Deep brain stimulation Deep Brain Stimulation - instrumentation Deep Brain Stimulation - methods Drug Resistant Epilepsy - physiopathology Drug Resistant Epilepsy - therapy Electrical stimuli Electrodes, Implanted Electroencephalography - instrumentation Electroencephalography - methods Epilepsy Evaluation Female Humans Male Oscillations Propagation Seizures Solitary tract nucleus Stereotaxic Techniques - instrumentation Stimulation Subthalamic nucleus Subthalamic Nucleus - physiology Target recognition Young Adult
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