Cellular dependency analysis identifies genes implicated in Alzheimer’s disease (AD) as potential treatment targets

Background Genes involved in the progression of Alzheimer’s disease (AD) have been identified, but these genes have not been studied in the context of CRISPR knockouts and RNAi screens to reveal cell‐specific vulnerabilities. Method A list of 105 AD‐associated genes, found through genome‐wide associ...

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Veröffentlicht in:Alzheimer's & dementia 2020-12, Vol.16, p.n/a
Hauptverfasser: Jaladanki, Suraj K, Malave, Gabriel Santos, Huang, Kuan‐lin
Format: Artikel
Sprache:eng
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