Multi‐center analysis of practice patterns and outcomes of younger and older patients with mantle cell lymphoma in the rituximab era

Clinical outcomes and predictors of survival in patients with newly diagnosed mantle cell lymphoma (MCL) treated in the rituximab era (2000–2015) at 12 US academic centers were assessed to identify determinants of survival across age groups. Objectives were to characterize and compare practice patte...

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Veröffentlicht in:	American journal of hematology 2021-11, Vol.96 (11), p.1374-1384
Hauptverfasser:	Karmali, Reem, Switchenko, Jeffrey M., Goyal, Subir, Shanmugasundaram, Krithika, Churnetski, Michael C., Kolla, Bhaskar, Bachanova, Veronika, Gerson, James N., Barta, Stefan K., Gordon, Max J., Danilov, Alexey V., Grover, Natalie S., Epperla, Narendranath, Mathews, Stephanie, Burkart, Madelyn, Sawalha, Yazeed, Hill, Brian T., Ghosh, Nilanjan, Park, Steven I., Bond, David A., Maddocks, Kami J., Badar, Talha, Fenske, Timothy S., Hamadani, Mehdi, Guo, Jin, Malecek, Mary, Kahl, Brad S., Martin, Peter, Blum, Kristie A., Flowers, Christopher R., Cohen, Jonathon B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age Factors Aged Antineoplastic Agents, Immunological - therapeutic use Cytarabine Female Hematology Humans Immunotherapy Life Sciences & Biomedicine Lymphoma Lymphoma, Mantle-Cell - drug therapy Lymphoma, Mantle-Cell - epidemiology Male Mantle cell lymphoma Medical prognosis Middle Aged Monoclonal antibodies Multivariate analysis Patients Progression-Free Survival Retrospective Studies Rituximab Rituximab - therapeutic use Science & Technology Survival Analysis Targeted cancer therapy Treatment Outcome
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Beschreibung
Zusammenfassung:	Clinical outcomes and predictors of survival in patients with newly diagnosed mantle cell lymphoma (MCL) treated in the rituximab era (2000–2015) at 12 US academic centers were assessed to identify determinants of survival across age groups. Objectives were to characterize and compare practice patterns, outcomes and prognostic factors for survival in younger patients (age
ISSN:	0361-8609 1096-8652
DOI:	10.1002/ajh.26306