A Versatile Cryomicroneedle Patch for Traceable Photodynamic Therapy (Adv. Mater. 36/2024)

A Versatile Cryomicroneedle Patch for Traceable Photodynamic Therapy (Adv. Mater. 36/2024)

Versatile Cryomicroneedle Patches In article number 2400933, Peng Huang and co‐workers, integrated frozen microneedles and enzyme mineralization technology to preserve the activity and improve the bioavailability of photosensitizers and catalase. The prepared patch can penetrate the cuticle efficien...

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Veröffentlicht in:Advanced materials (Weinheim) 2024-09, Vol.36 (36), p.n/a
Hauptverfasser: Li, Yashi, Li, Xingxing, He, Gang, Ding, Rui, Li, Youyan, Chen, Peng‐Hang, Wang, Dong, Lin, Jing, Huang, Peng
Format: Artikel
Sprache:eng
Schlagworte:
biomimetic mineralization
cryomicroneedle patch
melanoma
traceable photodynamic therapy
tumor microenvironment
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Zusammenfassung:Versatile Cryomicroneedle Patches In article number 2400933, Peng Huang and co‐workers, integrated frozen microneedles and enzyme mineralization technology to preserve the activity and improve the bioavailability of photosensitizers and catalase. The prepared patch can penetrate the cuticle efficiently to deliver its payloads, which induced oxidative stress, boosting antitumor efficacy while minimizing side effects, making it a reliable option for traceable photodynamic therapy.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.202470286