JKAP relates to disease risk, severity, and Th1 and Th17 differentiation in Parkinson's disease

Objective JNK pathway‐associated phosphatase (JKAP) is previously reported to regulate immune/inflammatory process via T‐cell signaling, and closely involves in neurological diseases, while its implication in Parkinson's disease (PD) is unknown. Therefore, this study aimed to investigate the co...

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Veröffentlicht in:	Annals of clinical and translational neurology 2021-09, Vol.8 (9), p.1786-1795
Hauptverfasser:	Yang, Qingwei, Zhuang, Jingcong, Cai, Pingping, Li, Longling, Wang, Rong, Chen, Zhongjie
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antibodies Autoimmune diseases CD4-Positive T-Lymphocytes Cell Differentiation - physiology Cognitive ability Down-Regulation Dual-Specificity Phosphatases - blood Enrollments Enzymes Female Females Humans Lymphocyte Activation - physiology Lymphocytes Male Medical research Middle Aged Mitogen-Activated Protein Kinase Phosphatases - blood Nervous system Neurological disorders Parkinson Disease - blood Parkinson Disease - epidemiology Parkinson Disease - physiopathology Parkinson's disease Patient Acuity Patients Phosphatase Proteins Risk Th1 Cells Th17 Cells
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