Introduction to Kinase Antitargets

Kinases represent an important enzyme class in drug discovery. They control cellular communication via distinct signaling networks. This is tightly regulated through transfer of phosphate from high‐energy adenosine triphosphate (ATP) onto the hydroxyls of serine, threonine, or tyrosine residues in s...

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Bibliographische Detailangaben

1. Verfasser:	Munson, Mark C
Format:	Buchkapitel
Sprache:	eng
Schlagworte:	kinase review kinome oncology safety selectivity toxicity
Online-Zugang:	Volltext
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