Capillary and Microchip Electrophoresis
Capillary electrophoresis (CE) is a separation technique employed for the analysis of charged and uncharged species, ranging from small inorganic ions to complex biomolecules. The versatility of CE arises from the many modes of operation such as capillary zone electrophoresis, micellar electrokineti...
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creator | Blanes, Lucas Gabriel, Ellen Flávia Moreira Saito, Renata Mayumi Coltro, Wendell Karlos Tomazelli Cole, Nerida Doble, Philip Roux, Claude Santos, Robson Oliveira |
description | Capillary electrophoresis (CE) is a separation technique employed for the analysis of charged and uncharged species, ranging from small inorganic ions to complex biomolecules. The versatility of CE arises from the many modes of operation such as capillary zone electrophoresis, micellar electrokinetic capillary chromatography, isoelectric focusing, isotachophoresis, capillary electrochromatography and capillary gel electrophoresis. Microchip‐Capillary Electrophoresis (ME) is a miniaturised version of CE where the capillary is replaced by a chip capillary device, which was initially proposed in the early 1990s by Manz and co‐workers. ME offers other potential advantages, particularly for compounds of forensic significance. These include shorter analysis times and lower sample volumes, as well as the potential for creation of disposable devices and automation. Electrochemical detectors (amperometry and conductometry) are commonly used in ME devices due to their high sensitivity and relatively easy implementation. |
doi_str_mv | 10.1002/9781119373421.ch15 |
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The versatility of CE arises from the many modes of operation such as capillary zone electrophoresis, micellar electrokinetic capillary chromatography, isoelectric focusing, isotachophoresis, capillary electrochromatography and capillary gel electrophoresis. Microchip‐Capillary Electrophoresis (ME) is a miniaturised version of CE where the capillary is replaced by a chip capillary device, which was initially proposed in the early 1990s by Manz and co‐workers. ME offers other potential advantages, particularly for compounds of forensic significance. These include shorter analysis times and lower sample volumes, as well as the potential for creation of disposable devices and automation. Electrochemical detectors (amperometry and conductometry) are commonly used in ME devices due to their high sensitivity and relatively easy implementation.</description><identifier>ISBN: 1119978289</identifier><identifier>ISBN: 9781119978282</identifier><identifier>EISBN: 1119373425</identifier><identifier>EISBN: 9781119373421</identifier><identifier>DOI: 10.1002/9781119373421.ch15</identifier><language>eng</language><publisher>Chichester, UK: John Wiley & Sons, Inc</publisher><subject>capillary electrochromatography ; capillary electrophoresis ; capillary gel electrophoresis ; capillary zone electrophoresis ; electrochemical detectors ; forensic analysis ; isoelectric focusing ; isotachophoresis ; micellar electrokinetic capillary chromatography ; microchip‐capillary electrophoresis</subject><ispartof>Analytical Techniques in Forensic Science, 2021, p.407-423</ispartof><rights>Copyright © 2021 John Wiley & Sons, Inc. All rights reserved.</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>779,780,784,793,27925</link.rule.ids></links><search><contributor>Forbes, Shari</contributor><contributor>Wolstenholme, Rosalind</contributor><contributor>Jickells, Susan</contributor><creatorcontrib>Blanes, Lucas</creatorcontrib><creatorcontrib>Gabriel, Ellen Flávia Moreira</creatorcontrib><creatorcontrib>Saito, Renata Mayumi</creatorcontrib><creatorcontrib>Coltro, Wendell Karlos Tomazelli</creatorcontrib><creatorcontrib>Cole, Nerida</creatorcontrib><creatorcontrib>Doble, Philip</creatorcontrib><creatorcontrib>Roux, Claude</creatorcontrib><creatorcontrib>Santos, Robson Oliveira</creatorcontrib><title>Capillary and Microchip Electrophoresis</title><title>Analytical Techniques in Forensic Science</title><description>Capillary electrophoresis (CE) is a separation technique employed for the analysis of charged and uncharged species, ranging from small inorganic ions to complex biomolecules. The versatility of CE arises from the many modes of operation such as capillary zone electrophoresis, micellar electrokinetic capillary chromatography, isoelectric focusing, isotachophoresis, capillary electrochromatography and capillary gel electrophoresis. Microchip‐Capillary Electrophoresis (ME) is a miniaturised version of CE where the capillary is replaced by a chip capillary device, which was initially proposed in the early 1990s by Manz and co‐workers. ME offers other potential advantages, particularly for compounds of forensic significance. These include shorter analysis times and lower sample volumes, as well as the potential for creation of disposable devices and automation. Electrochemical detectors (amperometry and conductometry) are commonly used in ME devices due to their high sensitivity and relatively easy implementation.</description><subject>capillary electrochromatography</subject><subject>capillary electrophoresis</subject><subject>capillary gel electrophoresis</subject><subject>capillary zone electrophoresis</subject><subject>electrochemical detectors</subject><subject>forensic analysis</subject><subject>isoelectric focusing</subject><subject>isotachophoresis</subject><subject>micellar electrokinetic capillary chromatography</subject><subject>microchip‐capillary electrophoresis</subject><isbn>1119978289</isbn><isbn>9781119978282</isbn><isbn>1119373425</isbn><isbn>9781119373421</isbn><fulltext>true</fulltext><rsrctype>book_chapter</rsrctype><creationdate>2021</creationdate><recordtype>book_chapter</recordtype><sourceid/><recordid>eNpjYJAyNNAzNDAw0rc0tzA0NLQ0Njc2MTLUS84wNGVk4IKLmDJDOEBVRhaWHAy8xcVZBkBtJgYWFgaGnAzqzokFmTk5iUWVCol5KQq-mclF-ckZmQUKrjmpySVF-QUZ-UWpxZnFPAysaYk5xam8UJqbwdjNNcTZQ7c8Mye1Mj41KT8_uzje0CAe5KZ4FDfFg9wEJozJ0wUAS88-4g</recordid><startdate>20210105</startdate><enddate>20210105</enddate><creator>Blanes, Lucas</creator><creator>Gabriel, Ellen Flávia Moreira</creator><creator>Saito, Renata Mayumi</creator><creator>Coltro, Wendell Karlos Tomazelli</creator><creator>Cole, Nerida</creator><creator>Doble, Philip</creator><creator>Roux, Claude</creator><creator>Santos, Robson Oliveira</creator><general>John Wiley & Sons, Inc</general><scope/></search><sort><creationdate>20210105</creationdate><title>Capillary and Microchip Electrophoresis</title><author>Blanes, Lucas ; Gabriel, Ellen Flávia Moreira ; Saito, Renata Mayumi ; Coltro, Wendell Karlos Tomazelli ; Cole, Nerida ; Doble, Philip ; Roux, Claude ; Santos, Robson Oliveira</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-wiley_ebooks_10_1002_9781119373421_ch15_ch153</frbrgroupid><rsrctype>book_chapters</rsrctype><prefilter>book_chapters</prefilter><language>eng</language><creationdate>2021</creationdate><topic>capillary electrochromatography</topic><topic>capillary electrophoresis</topic><topic>capillary gel electrophoresis</topic><topic>capillary zone electrophoresis</topic><topic>electrochemical detectors</topic><topic>forensic analysis</topic><topic>isoelectric focusing</topic><topic>isotachophoresis</topic><topic>micellar electrokinetic capillary chromatography</topic><topic>microchip‐capillary electrophoresis</topic><toplevel>online_resources</toplevel><creatorcontrib>Blanes, Lucas</creatorcontrib><creatorcontrib>Gabriel, Ellen Flávia Moreira</creatorcontrib><creatorcontrib>Saito, Renata Mayumi</creatorcontrib><creatorcontrib>Coltro, Wendell Karlos Tomazelli</creatorcontrib><creatorcontrib>Cole, Nerida</creatorcontrib><creatorcontrib>Doble, Philip</creatorcontrib><creatorcontrib>Roux, Claude</creatorcontrib><creatorcontrib>Santos, Robson Oliveira</creatorcontrib></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Blanes, Lucas</au><au>Gabriel, Ellen Flávia Moreira</au><au>Saito, Renata Mayumi</au><au>Coltro, Wendell Karlos Tomazelli</au><au>Cole, Nerida</au><au>Doble, Philip</au><au>Roux, Claude</au><au>Santos, Robson Oliveira</au><au>Forbes, Shari</au><au>Wolstenholme, Rosalind</au><au>Jickells, Susan</au><format>book</format><genre>bookitem</genre><ristype>CHAP</ristype><atitle>Capillary and Microchip Electrophoresis</atitle><btitle>Analytical Techniques in Forensic Science</btitle><date>2021-01-05</date><risdate>2021</risdate><spage>407</spage><epage>423</epage><pages>407-423</pages><isbn>1119978289</isbn><isbn>9781119978282</isbn><eisbn>1119373425</eisbn><eisbn>9781119373421</eisbn><abstract>Capillary electrophoresis (CE) is a separation technique employed for the analysis of charged and uncharged species, ranging from small inorganic ions to complex biomolecules. The versatility of CE arises from the many modes of operation such as capillary zone electrophoresis, micellar electrokinetic capillary chromatography, isoelectric focusing, isotachophoresis, capillary electrochromatography and capillary gel electrophoresis. Microchip‐Capillary Electrophoresis (ME) is a miniaturised version of CE where the capillary is replaced by a chip capillary device, which was initially proposed in the early 1990s by Manz and co‐workers. ME offers other potential advantages, particularly for compounds of forensic significance. These include shorter analysis times and lower sample volumes, as well as the potential for creation of disposable devices and automation. Electrochemical detectors (amperometry and conductometry) are commonly used in ME devices due to their high sensitivity and relatively easy implementation.</abstract><cop>Chichester, UK</cop><pub>John Wiley & Sons, Inc</pub><doi>10.1002/9781119373421.ch15</doi><tpages>17</tpages></addata></record> |
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language | eng |
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source | Ebook Central - Academic Complete; eBooks on EBSCOhost |
subjects | capillary electrochromatography capillary electrophoresis capillary gel electrophoresis capillary zone electrophoresis electrochemical detectors forensic analysis isoelectric focusing isotachophoresis micellar electrokinetic capillary chromatography microchip‐capillary electrophoresis |
title | Capillary and Microchip Electrophoresis |
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