Metabolism: Principle, Methods, and Applications

Drug metabolism is divided into three phases: phase I (mainly oxidation), phase II (conjugation), and phase III (transport/elimination). This chapter discusses the role of these three phases in the disposition of drugs and of drug‐metabolizing enzymes (DMEs) in metabolic clearance, renal clearance,...

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Bibliographische Detailangaben

Format:	Buchkapitel
Sprache:	eng
Schlagworte:	drug metabolism drug safety drug‐metabolizing enzymes metabolic clearance species differences translational technology
Online-Zugang:	Volltext
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