Tykerb Discovery: A Dual EGFR and ERBB2 Tyrosine Kinase Inhibitor
This chapter contains sections titled: Introduction Early Efforts Established the Feasibility of Inhibiting ERBB2 and EGFR Tyrosine Kinase Activity as a Drug Intervention Approach Lead Optimization Efforts Produced Two Drug Candidates with the Desired Mechanism of Action: GW 2974 and GW 0277 Data Re...
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