Effects of Okadaic Acid on Embryonic Development of the Starfish Asterina pectinifera
The effects of okadaic acid, an inhibitor of protein phosphatases types 1 and 2A, from the sponge Halichondria okadai Kadota, on the embryonic development of the starfish Asterina pectinifera, were investigated. When cultured in okadaic acid from fertilization, the embryo divided synchronously witho...
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| Veröffentlicht in: | Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 1992-01, Vol.56 (7), p.1007-1011 |
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| container_issue | 7 |
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| container_title | Bioscience, biotechnology, and biochemistry |
| container_volume | 56 |
| creator | Ikegami, Susumu Kajiyama, Noboru Ozaki, Yoshihiro Ooe, Yasunori Shimizu, Takahiko Kasahara, Toshihiko Uemura, Daisuke Shioda, Masaki |
| description | The effects of okadaic acid, an inhibitor of protein phosphatases types 1 and 2A, from the sponge Halichondria okadai Kadota, on the embryonic development of the starfish Asterina pectinifera, were investigated. When cultured in okadaic acid from fertilization, the embryo divided synchronously without any abnormalities such as lysis, swelling or morphological changes different from control embryos up to the 32-cell stage. However, okadaic acid prevented development before the onset of blastulation. Cytological examination showed that chromosomes condensed but did not align in a plane in the mitotic apparatus in each of the blastomeres of the treated embryo at the sixth cleavage, suggesting that this was the root cause of the arrest of further development. |
| doi_str_mv | 10.1271/bbb.56.1007 |
| format | Article |
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| identifier | ISSN: 0916-8451 |
| ispartof | Bioscience, biotechnology, and biochemistry, 1992-01, Vol.56 (7), p.1007-1011 |
| issn | 0916-8451 1347-6947 |
| language | eng |
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| source | J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; Open Access Titles of Japan; EZB-FREE-00999 freely available EZB journals; Free Full-Text Journals in Chemistry |
| subjects | Biological and medical sciences Echinodermata Fundamental and applied biological sciences. Psychology Halichondria okadai Invertebrates Marine |
| title | Effects of Okadaic Acid on Embryonic Development of the Starfish Asterina pectinifera |
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