The acute effects of MK-801 on cerebral blood flow and tissue partial pressures of oxygen and carbon dioxide in conscious and alpha-chloralose anaesthetized rats

The dynamic effects of the non-competitive N-methyl- d-aspartate receptor antagonist, MK-801 [(+)-5-methyl-10,11-dihydro-5H-dibenzo{ a,d}cyclohepten-5,10-imine], on cerebral blood flow and tissue partial pressures of oxygen and carbon dioxide were investigated in the striatal and occipital regions o...

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Veröffentlicht in:	Neuroscience 1992, Vol.47 (4), p.959-965
Hauptverfasser:	Roussel, S., Pinard, E., Seylaz, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia, General Animals Biological and medical sciences Blood Pressure - drug effects Carbon Dioxide - analysis Carbon Dioxide - metabolism Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Cerebrovascular Circulation - drug effects Chloralose Consciousness Corpus Striatum - drug effects Corpus Striatum - physiology Dizocilpine Maleate - pharmacology Fundamental and applied biological sciences. Psychology Kinetics Life Sciences & Biomedicine Male Neurosciences Neurosciences & Neurology Occipital Lobe - drug effects Occipital Lobe - physiology Oxygen - analysis Oxygen - metabolism Partial Pressure Rats Rats, Inbred Strains Science & Technology Time Factors Vertebrates: nervous system and sense organs
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