Adverse Events Following COVID-19 Vaccine in Patients Previously Injected with Facial Filler: Scoping Review and Case Report
The "Vaccines and Related Biological Products Advisory Committee 17 December 2020 Meeting Briefing Document", formulated by the FDA, reported three cases of swelling in areas previously injected with HA filler, introducing the possible relationship between a COVID-19 vaccine and adverse ev...
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| Veröffentlicht in: | Applied sciences 2021-11, Vol.11 (22), p.10888, Article 10888 |
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| creator | Rauso, Raffaele Lo Giudice, Giorgio Zerbinati, Nicola Nicoletti, Giovanni Francesco Fragola, Romolo Tartaro, Gianpaolo |
| description | The "Vaccines and Related Biological Products Advisory Committee 17 December 2020 Meeting Briefing Document", formulated by the FDA, reported three cases of swelling in areas previously injected with HA filler, introducing the possible relationship between a COVID-19 vaccine and adverse events in areas previously injected with HA fillers. The aim of this research is to report a case of an adverse event following a COVID-19 vaccine in a patient previously injected with facial filler. Furthermore, a scoping review on the same topic was performed. The research was carried out on the electronic databases PubMed, Cochrane Library, Web of Science, Google Scholar and Scopus. The selection process identified four articles as eligible for inclusion in the review. Nineteen patients, including the described case report, who experienced an adverse event following a COVID-19 vaccine in areas previously injected with facial filler were identified. Adverse events following a COVID-19 vaccine in patients previously injected with facial filler appear to be rare. A high BDDE cross-linking rate and/or a low-molecular-weight hyaluronic acid filler may have a higher tardive adverse event rate when triggered. |
| doi_str_mv | 10.3390/app112210888 |
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The aim of this research is to report a case of an adverse event following a COVID-19 vaccine in a patient previously injected with facial filler. Furthermore, a scoping review on the same topic was performed. The research was carried out on the electronic databases PubMed, Cochrane Library, Web of Science, Google Scholar and Scopus. The selection process identified four articles as eligible for inclusion in the review. Nineteen patients, including the described case report, who experienced an adverse event following a COVID-19 vaccine in areas previously injected with facial filler were identified. Adverse events following a COVID-19 vaccine in patients previously injected with facial filler appear to be rare. A high BDDE cross-linking rate and/or a low-molecular-weight hyaluronic acid filler may have a higher tardive adverse event rate when triggered.</description><identifier>ISSN: 2076-3417</identifier><identifier>EISSN: 2076-3417</identifier><identifier>DOI: 10.3390/app112210888</identifier><language>eng</language><publisher>BASEL: Mdpi</publisher><subject>adverse reaction ; Case reports ; Chemistry ; Chemistry, Multidisciplinary ; Coronaviruses ; COVID-19 ; COVID-19 vaccines ; Crosslinking ; Dermal fillers ; Edema ; Engineering ; Engineering, Multidisciplinary ; filler ; Fillers ; Hyaluronic acid ; Injections ; Materials Science ; Materials Science, Multidisciplinary ; Pandemics ; Patients ; Physical Sciences ; Physics ; Physics, Applied ; SARS-CoV-2 ; Science & Technology ; Technology ; Vaccines</subject><ispartof>Applied sciences, 2021-11, Vol.11 (22), p.10888, Article 10888</ispartof><rights>2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>8</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000778205300041</woscitedreferencesoriginalsourcerecordid><citedby>FETCH-LOGICAL-c367t-1d274afc82bad190ca66b6f3abec236a1cb2bdad06ceaaaa13c26430740b87c33</citedby><cites>FETCH-LOGICAL-c367t-1d274afc82bad190ca66b6f3abec236a1cb2bdad06ceaaaa13c26430740b87c33</cites><orcidid>0000-0002-8289-5527 ; 0000-0002-4497-3563 ; 0000-0001-9944-1073</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,866,2104,2116,27931,27932,39265</link.rule.ids></links><search><creatorcontrib>Rauso, Raffaele</creatorcontrib><creatorcontrib>Lo Giudice, Giorgio</creatorcontrib><creatorcontrib>Zerbinati, Nicola</creatorcontrib><creatorcontrib>Nicoletti, Giovanni Francesco</creatorcontrib><creatorcontrib>Fragola, Romolo</creatorcontrib><creatorcontrib>Tartaro, Gianpaolo</creatorcontrib><title>Adverse Events Following COVID-19 Vaccine in Patients Previously Injected with Facial Filler: Scoping Review and Case Report</title><title>Applied sciences</title><addtitle>APPL SCI-BASEL</addtitle><description>The "Vaccines and Related Biological Products Advisory Committee 17 December 2020 Meeting Briefing Document", formulated by the FDA, reported three cases of swelling in areas previously injected with HA filler, introducing the possible relationship between a COVID-19 vaccine and adverse events in areas previously injected with HA fillers. 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| subjects | adverse reaction Case reports Chemistry Chemistry, Multidisciplinary Coronaviruses COVID-19 COVID-19 vaccines Crosslinking Dermal fillers Edema Engineering Engineering, Multidisciplinary filler Fillers Hyaluronic acid Injections Materials Science Materials Science, Multidisciplinary Pandemics Patients Physical Sciences Physics Physics, Applied SARS-CoV-2 Science & Technology Technology Vaccines |
| title | Adverse Events Following COVID-19 Vaccine in Patients Previously Injected with Facial Filler: Scoping Review and Case Report |
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