Vitexin Inhibits Gastric Cancer Growth and Metastasis through HMGB1-mediated Inactivation of the PI3K/AKT/mTOR/HIF-1 alpha Signaling Pathway

Purpose: Gastric cancer (GC) has high morbidity and mortality and is a serious threat to public health. The flavonoid compound vitexin is known to exhibit anti-tumor activity. In this study, we explored the therapeutic potential of vitexin in GC and its underlying mechanism. Materials and Methods: T...

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Veröffentlicht in:Journal of gastric cancer 2021, 21(4), , pp.439-456
Hauptverfasser: Zhou, Peng, Zheng, Zi-Han, Wan, Tao, Wu, Jie, Liao, Chuan-Wen, Sun, Xue-Jun
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Sprache:eng
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