Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist

Unimolecular triple incretins, combining the activity of glucagon-like peptide-1 (GLP-1), glucose -dependent insulinotropic polypeptide (GIP), and glucagon (GCG), have demonstrated reduction in body weight and improved glucose control in rodent models. We developed SAR441255, a synthetic peptide ago...

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Veröffentlicht in:	New journal of chemistry 2021-11, p.59
Hauptverfasser:	Bossart, Martin, Wagner, Michael, Elvert, Ralf, Evers, Andreas, Hu, Thomas, Kloeckener, Tim, Lorenz, Katrin, Moessinger, Christine, Eriksson, Olof, Velikyan, Irina, Pierrou, Stefan, Johansson, Lars, Dietert, Gabriele, Dietz-Baum, Yasmin, Kissner, Thomas, Nowotny, Irene, Einig, Christine, Jan, Christelle, Rharbaoui, Faiza, Gassenhuber, Johann, Prochnow, Hans-Peter, Agueusop, Inoncent, Porksen, Niels, Smith, William B., Nitsche, Almut, Konkar, Anish
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Chemistry, Multidisciplinary Physical Sciences Science & Technology
Online-Zugang:	Volltext
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