Adipose Lipolysis Regulates Cardiac Glucose Uptake and Function in Mice under Cold Stress

The heart primarily uses fatty acids as energy substrates. Adipose lipolysis is a major source of fatty acids, particularly under stress conditions. In this study, we showed that mice with selective inactivation of the lipolytic coactivator comparative gene identification-58 (CGI-58) in adipose tiss...

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Veröffentlicht in:	International journal of molecular sciences 2021-12, Vol.22 (24), p.13361, Article 13361
Hauptverfasser:	Choi, Youngshim, Shin, Hyunsu, Tang, Ziwei, Yeh, Yute, Ma, Yinyan, Kadegowda, Anil K. G., Wang, Huan, Jiang, Long, Arya, Rakesh K., Chen, Ling, Xue, Bingzhong, Shi, Hang, Gavrilova, Oksana, Yu, Liqing
Format:	Artikel
Sprache:	eng
Schlagworte:	Abhd5 Acclimatization Adipocytes adipose lipolysis Adipose tissue Animals Atrial natriuretic peptide Biochemistry & Molecular Biology Body fat Body temperature Brain natriuretic peptide Ca2+-transporting ATPase Cadherins - deficiency Cadherins - metabolism Carbohydrates cardiac energy substrates and remodeling cardiac hypertrophy and dysfunction Chemistry Chemistry, Multidisciplinary Cold cold adaptation Cold-Shock Response Collagen (type I) Energy Energy resources Fatty acids Glucose Glucose - genetics Glucose - metabolism Glycerol Heart Heat Hypotheses Insulin Insulin resistance Life Sciences & Biomedicine Lipids Lipolysis Metabolism Metabolites Mice Mice, Knockout Mitochondria Mitochondria, Heart - genetics Mitochondria, Heart - metabolism Myocardium - metabolism Obesity Oxidative phosphorylation Peptides Phosphorylation Physical Sciences Proteins Rodents Science & Technology Thermogenesis
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