Curcumin protection against ultraviolet-induced photo-damage in Hacat cells by regulating nuclear factor erythroid 2-related factor 2

Curcumin suppressed ultraviolet (UV) induced skin carcinogenesis and activated the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway. However, whether curcumin protects skin injury caused by UV is still unknown. A vitro model was established and curcumin effects on Hacat cells were detected...

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Veröffentlicht in:	Bioengineered 2021-12, Vol.12 (2), p.9993-10006
Hauptverfasser:	Deng, Huiyan, Wan, Miaojian, Li, Huaping, Chen, Quan, Li, Runxiang, Liang, Bihua, Zhu, Huilan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants - metabolism Apoptosis - drug effects Apoptosis - radiation effects Biotechnology & Applied Microbiology Cell Nucleus - drug effects Cell Nucleus - metabolism Cell Nucleus - radiation effects Cell Proliferation - drug effects Cell Proliferation - radiation effects Cell Survival - drug effects Cell Survival - radiation effects Curcumin Curcumin - pharmacology Cytoprotection - drug effects Cytoprotection - radiation effects HaCaT Cells Humans Keratinocytes - drug effects Keratinocytes - metabolism Keratinocytes - pathology Keratinocytes - radiation effects Life Sciences & Biomedicine NF-E2-Related Factor 2 - metabolism nuclear factor erythroid 2-related factor 2 oxidative stress photo-damage Research Paper Science & Technology skin ultraviolet Ultraviolet Rays
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