Methylation of BDNF and SLC6A4 Gene Promoters in Brazilian Patients With Temporal Lobe Epilepsy Presenting or Not Psychiatric Comorbidities

The relationship between epilepsy and psychiatric comorbidities has been recognized for centuries, but its pathophysiological mechanisms are still misunderstood. It is biologically plausible that genetic or epigenetic variations in genes that codify important neurotransmitters involved in epilepsy a...

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Veröffentlicht in:	Frontiers in integrative neuroscience 2021-11, Vol.15, p.764742-764742, Article 764742
Hauptverfasser:	Bandeira, Isabel Cristina, Giombelli, Lucas, Werlang, Isabel Cristina, Abujamra, Ana Lucia, Secchi, Thais Leite, Brondani, Rosane, Bragatti, Jose Augusto, Bizzi, Jorge Wladimir Junqueira, Leistner-Segal, Sandra, Bianchin, Marino Muxfeldt
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Anxiety disorders BDNF Behavioral Sciences Brain-derived neurotrophic factor depression DNA methylation Drug abuse Emotional disorders Epigenetics Epilepsy Gene expression Genetic diversity Life Sciences & Biomedicine Mental disorders methylation Mood Mood disorders Nervous system Neural plasticity Neuroscience Neurosciences Neurosciences & Neurology Neurotransmitters neurotrophins Patients psychiatric comorbidities Psychosis Science & Technology Seizures Serotonin Temporal lobe
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