Mechanical stress affects dynamics and rheology of the human genome

Material properties of the genome are critical for proper cellular function - they directly affect timescales and length scales of DNA transactions such as transcription, replication and DNA repair, which in turn impact all cellular processes via the central dogma of molecular biology. Hence, elucid...

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Veröffentlicht in:	Soft matter 2021-12, Vol.18 (1), p.17-116
Hauptverfasser:	Caragine, Christina M, Kanellakopoulos, Nikitas, Zidovska, Alexandra
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Nucleus Chemistry Chemistry, Physical Deoxyribonucleic acid DNA DNA - genetics DNA biosynthesis DNA damage DNA probes DNA repair Genome, Human Genomes Genomics Humans Injection Material properties Materials Science Materials Science, Multidisciplinary Micrometers Molecular biology Nuclei (cytology) Physical Sciences Physics Physics, Multidisciplinary Polymer Science Probes Rheological properties Rheology Science & Technology Spectroscopy Stress Stress, Mechanical Technology Transcription
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