CHEMICAL COMPOSITION AND BIOLOGICAL ACTIVITIES OF VOLATILE OILS OF ARABIS ALPINA L. SSP. ALPINA

This work reports volatile constituents, antimicrobial and antioxidant activity of volatile oils from the air-dried flower and aerial parts (APs) of Arabis alpina L. ssp. alpina. The volatile components of flower and aerial parts (stem + leaf) were investigated by means of hydrodistillation in Clevenger type apparatus and GC/MS/FID analysis. Fifty-one and fifty-three compounds in the volatile oils of flower and APs of A. alpina were identified. Terpene derivatives were the major volatiles in both oils. Hexahydrofarnesyl acetone was the main component of flower oil and APs oil in ratios of 16.27% and 26.94%, respectively. Additionally, both flower and APs essential oils were investigated for their antimicrobial activity against twelve bacteria and five fungi, using agar dilution method and antioxidant activities by using DPPH center dot, ABTS(center dot+) and Folin-Ciocalteu assays. Flower oil was effective against B. subtilis and B. cereus even at 100 mu g/mL. The amount of total phenolic, %DPPH center dot scavenging activity and ABTS(center dot+) scavenging activity were found as 485.60 +/- 7.28 mg/mL GAE, 49.85 +/- 1.22% and 166.43 +/- 12.05 mu M Trolox equivalent, respectively. Flower oil exhibited antimicrobial effect against gram positive bacteria especially, and moderate antioxidant activity.