A Phase II Study to Assess the Safety and Efficacy of the Dual mTORC1/2 and PI3K Inhibitor Bimiralisib (PQR309) in Relapsed, Refractory Lymphoma

Supplemental Digital Content is available in the text. Bimiralisib is an orally bioavailable pan‐phosphatidylinositol 3‐kinase and mammalian target of rapamycin inhibitor which has shown activity against lymphoma in preclinical models. This phase I/II study evaluated the response rate to bimiralisib...

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Veröffentlicht in:HemaSphere 2021-11, Vol.5 (11), p.e656-n/a
Hauptverfasser: Collins, Graham P., Eyre, Toby A., Schmitz‐Rohmer, Debora, Townsend, William, Popat, Rakesh, Giulino‐Roth, Lisa, Fields, Paul A., Krasniqi, Fatime, Soussain, Carole, Stathis, Anastasios, Andjelkovic, Nebojsa, Cunningham, David, Mandic, Danijela, Radulovic, Sinisa, Tijanic, Ivan, Horowitz, Netanel A., Kurtovic, Sabira, Schorb, Elisabeth, Schmidt, Christian, Dimitrijević, Saša, Dreyling, Martin
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Sprache:eng
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