Targeting senescent retinal pigment epithelial cells facilitates retinal regeneration in mouse models of age-related macular degeneration

Although age-related macular degeneration (AMD) is a multifactorial disorder with angiogenic, immune, and inflammatory components, the most common clinical treatment strategies are antiangiogenic therapies. However, these strategies are only applicable to neovascular AMD, which accounts for less tha...

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Veröffentlicht in:GeroScience 2021-12, Vol.43 (6), p.2809-2833
Hauptverfasser: Chae, Jae-Byoung, Jang, Hyoik, Son, Chanok, Park, Chul-Woo, Choi, Huyeon, Jin, Seongeon, Lee, Ho-Yeon, Lee, Hyungwoo, Ryu, Ja-Hyoung, Kim, Namshin, Kim, Chaekyu, Chung, Hyewon
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Sprache:eng
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