Microstructural and mechanical characterization of the layers of human descending thoracic aortas

The mechanical properties of human aortas are linked to the layered tissue and its microstructure at different length scales. Each layer has specific mechanical and structural properties. While the ground substance and the elastin play an important role in tissue stiffness at small strain, collagen...

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Veröffentlicht in:	Acta biomaterialia 2021-10, Vol.134, p.401-421
Hauptverfasser:	Amabili, Marco, Asgari, Meisam, Breslavsky, Ivan D., Franchini, Giulio, Giovanniello, Francesco, Holzapfel, Gerhard A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aorta Atomic force microscopy Bivariate analysis Blood flow Blood pressure Collagen Coronary vessels Diameters Dispersion Elastic properties Elastin Engineering Engineering, Biomedical Experiments Fiber orientation Fibers Fluorescence Folding Genetic algorithms Heterogeneity Human aorta Hypertension Layer-specific Material model Materials Science Materials Science, Biomaterials Mechanical analysis Mechanical characterization Mechanical properties Microstructure Parameters Perfusion Risk analysis Risk factors Science & Technology Statistical analysis Stiffness Technology Tensile tests Thorax Tissues
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