Antioxidative and immunological effects of Cyclocarya paliurus polysaccharides on the spleen injury of diabetic rats
OBJEVTIVE: To investigate the effects of Cyclocarya paliurus (C. paliurus) polysaccharides on the spleen injury of diabetic rats. METHODS: Animals were divided into 6 groups, including normal group, model group, control group, low-dose group of C. paliurus polysaccharides treatment, middle-dose grou...
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| Veröffentlicht in: | Journal of traditional Chinese medicine 2021-10, Vol.41 (5), p.739-746 |
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| container_title | Journal of traditional Chinese medicine |
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| creator | Xia Xichao Li Bin Qiu Ju Tian Gang Chen Changdong La Ming Zhang Ke Qi Jinxu Li Yanyan Gao Huashan Shao Xiangyang Su Congying Wang Mengqi Ouyang Jingfeng |
| description | OBJEVTIVE: To investigate the effects of Cyclocarya paliurus (C. paliurus) polysaccharides on the spleen injury of diabetic rats.
METHODS: Animals were divided into 6 groups, including normal group, model group, control group, low-dose group of C. paliurus polysaccharides treatment, middle-dose group of C. paliurus polysaccharides treatment and high-dose group of C. paliurus polysaccharides treatment. Histological analysis of spleen was analyzed using hematoxilin and eosin. Levels of biological parameters and anti-oxidative enzymes were determined by spectrophotometry. Interleukin-7 (IL-7) and IL-10 were measured by enzyme-linked immunosorbent assay.
RESULTS: Compared with that of model group, superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase level increased 78.63% (P < 0.05), 51.76% (P < 0.05), 2.95 times (P < 0.01) and 41.11% (P < 0.05) in the high-dose group of C. paliurus polysaccharides treatment, respectively. IL-7 and IL-10 increase 1.66 (P < 0.01) and 1.21 times (P < 0.01) in the high-dose group of C. paliurus polysaccharides treatment, respectively.
CONCLUSION: It is suggested that C. paliurus polysaccharides may play a protecting role for spleen injury of diabetic rats by enhancing the antioxidative ability and evaluating the immunity. (C) 2021 JTCM. All rights reserved. |
| doi_str_mv | 10.19852/j.cnki.jtcm.20210203.001 |
| format | Article |
| fullrecord | <record><control><sourceid>webofscience</sourceid><recordid>TN_cdi_webofscience_primary_000707994400010</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>000707994400010</sourcerecordid><originalsourceid>FETCH-LOGICAL-s155t-f5163c8cdbc0298b662a4faac1d4e4cca799311ba18beeca8f1d34514e5d6b3c3</originalsourceid><addsrcrecordid>eNqNkM9OhDAYxBujievqO9SzAdtCoRw3xH_JJl70vPn4aN0itIQWlbcXow_gaebwm0lmCLnmLOWVkuK2S9G927SLOKSCCc4Ey1LG-AnZcFmWScl4fko2TEiZiEqIc3IRQseYVFKqDYk7F63_si1E-6EpuJbaYZid7_2bReipNkZjDNQbWi_Ye4RpATpCb-dpDnT0_RIA8QiTbfWKORqPmoax19pR67p5Wn6yrYVGR4t0ghguyZmBPuirP92S1_u7l_ox2T8_PNW7fRK4lDExkhcZKmwbZKJSTVEIyA0A8jbXOSKUVZVx3gBXjdYIyvA2yyXPtWyLJsNsS25-ez91401Aqx3qwzjZYR1xYIyVbK3I89VxttLq_3Rt4_qYd7WfXcy-AXpneRk</addsrcrecordid><sourcetype>Enrichment Source</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Antioxidative and immunological effects of Cyclocarya paliurus polysaccharides on the spleen injury of diabetic rats</title><source>Web of Science - Science Citation Index Expanded - 2021<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" /></source><source>Alma/SFX Local Collection</source><source>EZB Electronic Journals Library</source><creator>Xia Xichao ; Li Bin ; Qiu Ju ; Tian Gang ; Chen Changdong ; La Ming ; Zhang Ke ; Qi Jinxu ; Li Yanyan ; Gao Huashan ; Shao Xiangyang ; Su Congying ; Wang Mengqi ; Ouyang Jingfeng</creator><creatorcontrib>Xia Xichao ; Li Bin ; Qiu Ju ; Tian Gang ; Chen Changdong ; La Ming ; Zhang Ke ; Qi Jinxu ; Li Yanyan ; Gao Huashan ; Shao Xiangyang ; Su Congying ; Wang Mengqi ; Ouyang Jingfeng</creatorcontrib><description><![CDATA[OBJEVTIVE: To investigate the effects of Cyclocarya paliurus (C. paliurus) polysaccharides on the spleen injury of diabetic rats.
METHODS: Animals were divided into 6 groups, including normal group, model group, control group, low-dose group of C. paliurus polysaccharides treatment, middle-dose group of C. paliurus polysaccharides treatment and high-dose group of C. paliurus polysaccharides treatment. Histological analysis of spleen was analyzed using hematoxilin and eosin. Levels of biological parameters and anti-oxidative enzymes were determined by spectrophotometry. Interleukin-7 (IL-7) and IL-10 were measured by enzyme-linked immunosorbent assay.
RESULTS: Compared with that of model group, superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase level increased 78.63% (P < 0.05), 51.76% (P < 0.05), 2.95 times (P < 0.01) and 41.11% (P < 0.05) in the high-dose group of C. paliurus polysaccharides treatment, respectively. IL-7 and IL-10 increase 1.66 (P < 0.01) and 1.21 times (P < 0.01) in the high-dose group of C. paliurus polysaccharides treatment, respectively.
CONCLUSION: It is suggested that C. paliurus polysaccharides may play a protecting role for spleen injury of diabetic rats by enhancing the antioxidative ability and evaluating the immunity. (C) 2021 JTCM. All rights reserved.]]></description><identifier>ISSN: 0255-2922</identifier><identifier>EISSN: 1577-7014</identifier><identifier>DOI: 10.19852/j.cnki.jtcm.20210203.001</identifier><language>eng</language><publisher>BEIJING: Journal Traditional Chinese Med</publisher><subject>Integrative & Complementary Medicine ; Life Sciences & Biomedicine ; Science & Technology</subject><ispartof>Journal of traditional Chinese medicine, 2021-10, Vol.41 (5), p.739-746</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>0</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000707994400010</woscitedreferencesoriginalsourcerecordid><cites>FETCH-LOGICAL-s155t-f5163c8cdbc0298b662a4faac1d4e4cca799311ba18beeca8f1d34514e5d6b3c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930,39263</link.rule.ids></links><search><creatorcontrib>Xia Xichao</creatorcontrib><creatorcontrib>Li Bin</creatorcontrib><creatorcontrib>Qiu Ju</creatorcontrib><creatorcontrib>Tian Gang</creatorcontrib><creatorcontrib>Chen Changdong</creatorcontrib><creatorcontrib>La Ming</creatorcontrib><creatorcontrib>Zhang Ke</creatorcontrib><creatorcontrib>Qi Jinxu</creatorcontrib><creatorcontrib>Li Yanyan</creatorcontrib><creatorcontrib>Gao Huashan</creatorcontrib><creatorcontrib>Shao Xiangyang</creatorcontrib><creatorcontrib>Su Congying</creatorcontrib><creatorcontrib>Wang Mengqi</creatorcontrib><creatorcontrib>Ouyang Jingfeng</creatorcontrib><title>Antioxidative and immunological effects of Cyclocarya paliurus polysaccharides on the spleen injury of diabetic rats</title><title>Journal of traditional Chinese medicine</title><addtitle>J TRADIT CHIN MED</addtitle><description><![CDATA[OBJEVTIVE: To investigate the effects of Cyclocarya paliurus (C. paliurus) polysaccharides on the spleen injury of diabetic rats.
METHODS: Animals were divided into 6 groups, including normal group, model group, control group, low-dose group of C. paliurus polysaccharides treatment, middle-dose group of C. paliurus polysaccharides treatment and high-dose group of C. paliurus polysaccharides treatment. Histological analysis of spleen was analyzed using hematoxilin and eosin. Levels of biological parameters and anti-oxidative enzymes were determined by spectrophotometry. Interleukin-7 (IL-7) and IL-10 were measured by enzyme-linked immunosorbent assay.
RESULTS: Compared with that of model group, superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase level increased 78.63% (P < 0.05), 51.76% (P < 0.05), 2.95 times (P < 0.01) and 41.11% (P < 0.05) in the high-dose group of C. paliurus polysaccharides treatment, respectively. IL-7 and IL-10 increase 1.66 (P < 0.01) and 1.21 times (P < 0.01) in the high-dose group of C. paliurus polysaccharides treatment, respectively.
CONCLUSION: It is suggested that C. paliurus polysaccharides may play a protecting role for spleen injury of diabetic rats by enhancing the antioxidative ability and evaluating the immunity. (C) 2021 JTCM. All rights reserved.]]></description><subject>Integrative & Complementary Medicine</subject><subject>Life Sciences & Biomedicine</subject><subject>Science & Technology</subject><issn>0255-2922</issn><issn>1577-7014</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>HGBXW</sourceid><recordid>eNqNkM9OhDAYxBujievqO9SzAdtCoRw3xH_JJl70vPn4aN0itIQWlbcXow_gaebwm0lmCLnmLOWVkuK2S9G927SLOKSCCc4Ey1LG-AnZcFmWScl4fko2TEiZiEqIc3IRQseYVFKqDYk7F63_si1E-6EpuJbaYZid7_2bReipNkZjDNQbWi_Ye4RpATpCb-dpDnT0_RIA8QiTbfWKORqPmoax19pR67p5Wn6yrYVGR4t0ghguyZmBPuirP92S1_u7l_ox2T8_PNW7fRK4lDExkhcZKmwbZKJSTVEIyA0A8jbXOSKUVZVx3gBXjdYIyvA2yyXPtWyLJsNsS25-ez91401Aqx3qwzjZYR1xYIyVbK3I89VxttLq_3Rt4_qYd7WfXcy-AXpneRk</recordid><startdate>20211015</startdate><enddate>20211015</enddate><creator>Xia Xichao</creator><creator>Li Bin</creator><creator>Qiu Ju</creator><creator>Tian Gang</creator><creator>Chen Changdong</creator><creator>La Ming</creator><creator>Zhang Ke</creator><creator>Qi Jinxu</creator><creator>Li Yanyan</creator><creator>Gao Huashan</creator><creator>Shao Xiangyang</creator><creator>Su Congying</creator><creator>Wang Mengqi</creator><creator>Ouyang Jingfeng</creator><general>Journal Traditional Chinese Med</general><scope>BLEPL</scope><scope>DTL</scope><scope>HGBXW</scope></search><sort><creationdate>20211015</creationdate><title>Antioxidative and immunological effects of Cyclocarya paliurus polysaccharides on the spleen injury of diabetic rats</title><author>Xia Xichao ; Li Bin ; Qiu Ju ; Tian Gang ; Chen Changdong ; La Ming ; Zhang Ke ; Qi Jinxu ; Li Yanyan ; Gao Huashan ; Shao Xiangyang ; Su Congying ; Wang Mengqi ; Ouyang Jingfeng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-s155t-f5163c8cdbc0298b662a4faac1d4e4cca799311ba18beeca8f1d34514e5d6b3c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Integrative & Complementary Medicine</topic><topic>Life Sciences & Biomedicine</topic><topic>Science & Technology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Xia Xichao</creatorcontrib><creatorcontrib>Li Bin</creatorcontrib><creatorcontrib>Qiu Ju</creatorcontrib><creatorcontrib>Tian Gang</creatorcontrib><creatorcontrib>Chen Changdong</creatorcontrib><creatorcontrib>La Ming</creatorcontrib><creatorcontrib>Zhang Ke</creatorcontrib><creatorcontrib>Qi Jinxu</creatorcontrib><creatorcontrib>Li Yanyan</creatorcontrib><creatorcontrib>Gao Huashan</creatorcontrib><creatorcontrib>Shao Xiangyang</creatorcontrib><creatorcontrib>Su Congying</creatorcontrib><creatorcontrib>Wang Mengqi</creatorcontrib><creatorcontrib>Ouyang Jingfeng</creatorcontrib><collection>Web of Science Core Collection</collection><collection>Science Citation Index Expanded</collection><collection>Web of Science - Science Citation Index Expanded - 2021</collection><jtitle>Journal of traditional Chinese medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Xia Xichao</au><au>Li Bin</au><au>Qiu Ju</au><au>Tian Gang</au><au>Chen Changdong</au><au>La Ming</au><au>Zhang Ke</au><au>Qi Jinxu</au><au>Li Yanyan</au><au>Gao Huashan</au><au>Shao Xiangyang</au><au>Su Congying</au><au>Wang Mengqi</au><au>Ouyang Jingfeng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antioxidative and immunological effects of Cyclocarya paliurus polysaccharides on the spleen injury of diabetic rats</atitle><jtitle>Journal of traditional Chinese medicine</jtitle><stitle>J TRADIT CHIN MED</stitle><date>2021-10-15</date><risdate>2021</risdate><volume>41</volume><issue>5</issue><spage>739</spage><epage>746</epage><pages>739-746</pages><issn>0255-2922</issn><eissn>1577-7014</eissn><abstract><![CDATA[OBJEVTIVE: To investigate the effects of Cyclocarya paliurus (C. paliurus) polysaccharides on the spleen injury of diabetic rats.
METHODS: Animals were divided into 6 groups, including normal group, model group, control group, low-dose group of C. paliurus polysaccharides treatment, middle-dose group of C. paliurus polysaccharides treatment and high-dose group of C. paliurus polysaccharides treatment. Histological analysis of spleen was analyzed using hematoxilin and eosin. Levels of biological parameters and anti-oxidative enzymes were determined by spectrophotometry. Interleukin-7 (IL-7) and IL-10 were measured by enzyme-linked immunosorbent assay.
RESULTS: Compared with that of model group, superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase level increased 78.63% (P < 0.05), 51.76% (P < 0.05), 2.95 times (P < 0.01) and 41.11% (P < 0.05) in the high-dose group of C. paliurus polysaccharides treatment, respectively. IL-7 and IL-10 increase 1.66 (P < 0.01) and 1.21 times (P < 0.01) in the high-dose group of C. paliurus polysaccharides treatment, respectively.
CONCLUSION: It is suggested that C. paliurus polysaccharides may play a protecting role for spleen injury of diabetic rats by enhancing the antioxidative ability and evaluating the immunity. (C) 2021 JTCM. All rights reserved.]]></abstract><cop>BEIJING</cop><pub>Journal Traditional Chinese Med</pub><doi>10.19852/j.cnki.jtcm.20210203.001</doi><tpages>8</tpages></addata></record> |
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| subjects | Integrative & Complementary Medicine Life Sciences & Biomedicine Science & Technology |
| title | Antioxidative and immunological effects of Cyclocarya paliurus polysaccharides on the spleen injury of diabetic rats |
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