Postmitotic Prox1 Expression Controls the Final Specification of Cortical VIP Interneuron Subtypes

Throughout development, neuronal identity is controlled by key transcription factors that determine the unique properties of a cell. During embryogenesis, the transcription factor Prox1 regulates VIP-positive cortical interneuron migration, survival, and connectivity. Here, we explore the role of Pr...

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Veröffentlicht in:	The Journal of neuroscience 2021-09, Vol.41 (39), p.8150-8162
Hauptverfasser:	Stachniak, Tevye Jason, Kastli, Rahel, Hanley, Olivia, Argunsah, Ali Özgür, van der Valk, Elianne Grietje Theodora, Kanatouris, George, Karayannis, Theofanis
Format:	Artikel
Sprache:	eng
Schlagworte:	Bipolar cells Electrophysiology Embryogenesis Embryonic growth stage Gene expression Gene sequencing Genetic programs Neural networks Post-transcription Specifications Transcription factors
Online-Zugang:	Volltext
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