Behcet's Disease with Extremely High Levels of Urinary beta 2-Microglobulin after Non-Steroidal Anti-Inflammatory Drug Treatment

Behcet's disease is an inflammatory disease which manifests itself as various symptoms, such as uveitis, oral and genital aphthae, erythema nodosa, gastro-intestinal ulcerations and encephalopathy. Among the manifestations, renal dysfunction is reported in some percentage of the patients with t...

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Veröffentlicht in:Tohoku journal of experimental medicine 2021-08, Vol.254 (4), p.283-286
Hauptverfasser: Ogino, Ryohei, Shimada, Karin, Narai, Daiki, Goto, Masanori, Sato, Katsuhiro, Katsuta, Yoshihisa, Shiigi, Akimasa, Ueda, Juri, Oyama, Chika, Fujikawa, Yuko, Miyazawa, Isabelle, Ohara, Takahiro, Sumitomo, Kazuhiro, Sato, Shigeru, Koinuma, Nobuo, Kanno, Atsuhiro, Furukawa, Katsutoshi
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container_issue 4
container_start_page 283
container_title Tohoku journal of experimental medicine
container_volume 254
creator Ogino, Ryohei
Shimada, Karin
Narai, Daiki
Goto, Masanori
Sato, Katsuhiro
Katsuta, Yoshihisa
Shiigi, Akimasa
Ueda, Juri
Oyama, Chika
Fujikawa, Yuko
Miyazawa, Isabelle
Ohara, Takahiro
Sumitomo, Kazuhiro
Sato, Shigeru
Koinuma, Nobuo
Kanno, Atsuhiro
Furukawa, Katsutoshi
description Behcet's disease is an inflammatory disease which manifests itself as various symptoms, such as uveitis, oral and genital aphthae, erythema nodosa, gastro-intestinal ulcerations and encephalopathy. Among the manifestations, renal dysfunction is reported in some percentage of the patients with this disorder. We experienced a middle-aged male with Behcet's disease who showed an extremely high level of urinary beta 2-microglulin, which is one of the markers of renal dysfunction, despite normal serum creatinine levels. The patient was on non-steroidal anti-inflammatory drug (NSAID) therapy for 7 weeks, and this could have affected his renal dysfunction. The present report suggests that renal injury should not be underestimated in patients with Behcet's disease, especially in patients using NSAIDs.
doi_str_mv 10.1620/tjem.254.283
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subjects General & Internal Medicine
Life Sciences & Biomedicine
Medicine, General & Internal
Medicine, Research & Experimental
Research & Experimental Medicine
Science & Technology
title Behcet's Disease with Extremely High Levels of Urinary beta 2-Microglobulin after Non-Steroidal Anti-Inflammatory Drug Treatment
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