Behcet's Disease with Extremely High Levels of Urinary beta 2-Microglobulin after Non-Steroidal Anti-Inflammatory Drug Treatment
Behcet's disease is an inflammatory disease which manifests itself as various symptoms, such as uveitis, oral and genital aphthae, erythema nodosa, gastro-intestinal ulcerations and encephalopathy. Among the manifestations, renal dysfunction is reported in some percentage of the patients with t...
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Veröffentlicht in: | Tohoku journal of experimental medicine 2021-08, Vol.254 (4), p.283-286 |
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container_title | Tohoku journal of experimental medicine |
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creator | Ogino, Ryohei Shimada, Karin Narai, Daiki Goto, Masanori Sato, Katsuhiro Katsuta, Yoshihisa Shiigi, Akimasa Ueda, Juri Oyama, Chika Fujikawa, Yuko Miyazawa, Isabelle Ohara, Takahiro Sumitomo, Kazuhiro Sato, Shigeru Koinuma, Nobuo Kanno, Atsuhiro Furukawa, Katsutoshi |
description | Behcet's disease is an inflammatory disease which manifests itself as various symptoms, such as uveitis, oral and genital aphthae, erythema nodosa, gastro-intestinal ulcerations and encephalopathy. Among the manifestations, renal dysfunction is reported in some percentage of the patients with this disorder. We experienced a middle-aged male with Behcet's disease who showed an extremely high level of urinary beta 2-microglulin, which is one of the markers of renal dysfunction, despite normal serum creatinine levels. The patient was on non-steroidal anti-inflammatory drug (NSAID) therapy for 7 weeks, and this could have affected his renal dysfunction. The present report suggests that renal injury should not be underestimated in patients with Behcet's disease, especially in patients using NSAIDs. |
doi_str_mv | 10.1620/tjem.254.283 |
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Among the manifestations, renal dysfunction is reported in some percentage of the patients with this disorder. We experienced a middle-aged male with Behcet's disease who showed an extremely high level of urinary beta 2-microglulin, which is one of the markers of renal dysfunction, despite normal serum creatinine levels. The patient was on non-steroidal anti-inflammatory drug (NSAID) therapy for 7 weeks, and this could have affected his renal dysfunction. 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Among the manifestations, renal dysfunction is reported in some percentage of the patients with this disorder. We experienced a middle-aged male with Behcet's disease who showed an extremely high level of urinary beta 2-microglulin, which is one of the markers of renal dysfunction, despite normal serum creatinine levels. The patient was on non-steroidal anti-inflammatory drug (NSAID) therapy for 7 weeks, and this could have affected his renal dysfunction. 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Among the manifestations, renal dysfunction is reported in some percentage of the patients with this disorder. We experienced a middle-aged male with Behcet's disease who showed an extremely high level of urinary beta 2-microglulin, which is one of the markers of renal dysfunction, despite normal serum creatinine levels. The patient was on non-steroidal anti-inflammatory drug (NSAID) therapy for 7 weeks, and this could have affected his renal dysfunction. The present report suggests that renal injury should not be underestimated in patients with Behcet's disease, especially in patients using NSAIDs.</abstract><cop>SENDAI</cop><pub>Tohoku Univ Medical Press</pub><pmid>34433735</pmid><doi>10.1620/tjem.254.283</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | General & Internal Medicine Life Sciences & Biomedicine Medicine, General & Internal Medicine, Research & Experimental Research & Experimental Medicine Science & Technology |
title | Behcet's Disease with Extremely High Levels of Urinary beta 2-Microglobulin after Non-Steroidal Anti-Inflammatory Drug Treatment |
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