Cavitation-modulated inflammatory response following focused ultrasound blood-brain barrier opening

Focused ultrasound (FUS) in combination with systemically injected microbubbles can be used to non-invasively open the blood-brain barrier (BBB) in targeted regions for a variety of therapeutic applications. Over the past two decades, preclinical research into the safety and efficacy of FUS-induced...

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Veröffentlicht in:	Journal of controlled release 2021-09, Vol.337, p.458-471
Hauptverfasser:	Ji, Robin, Karakatsani, Maria E., Burgess, Mark, Smith, Morgan, Murillo, Maria F., Konofagou, Elisa E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood-Brain Barrier Brain drug delivery Cavitation controller Chemistry Chemistry, Multidisciplinary Drug Delivery Systems Focused ultrasound Inflammation Inflammatory response Life Sciences & Biomedicine Magnetic Resonance Imaging Mice Microbubbles Permeability Pharmacology & Pharmacy Physical Sciences Science & Technology Sonication - adverse effects Sonication - methods
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