CHSY1 is upregulated and acts as tumor promotor in gastric cancer through regulating cell proliferation, apoptosis, and migration

Gastric cancer is one of the most frequently diagnosed malignant tumors, with rapid progression and poor prognosis. The role of chondroitin sulfate synthase 1 (CHSY1) in the development and progression of gastric cancer was explored and clarified in this study. The immunohistochemistry analysis of c...

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Veröffentlicht in:	Cell cycle (Georgetown, Tex.) Tex.), 2021-09, Vol.20 (18), p.1861-1874
Hauptverfasser:	Liu, Jingjing, Tian, Zhenwei, Liu, Tianzhou, Wen, Dacheng, Ma, Zhiming, Liu, Yuanda, Zhu, Jiaming
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Animals Apoptosis - genetics Carcinogenesis - genetics Carcinogenesis - metabolism cell apoptosis Cell Line, Tumor cell migration Cell Movement - genetics cell proliferation Cell Proliferation - genetics CHSY1 Female Gastric cancer Gene Expression Regulation, Neoplastic Gene Knockdown Techniques - methods Glucuronosyltransferase - genetics Glucuronosyltransferase - metabolism Humans Mice Mice, Inbred BALB C Mice, Nude Middle Aged Multifunctional Enzymes - genetics Multifunctional Enzymes - metabolism N-Acetylgalactosaminyltransferases - genetics N-Acetylgalactosaminyltransferases - metabolism Prognosis Research Paper Stomach Neoplasms - genetics Stomach Neoplasms - metabolism Stomach Neoplasms - pathology Transfection - methods Tumor Burden - genetics Up-Regulation - genetics Xenograft Model Antitumor Assays - methods
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