The Amorphous Quercetin/ Hydroxypropylmethylcellulose Acetate Succinate Solid Dispersions Prepared by Co-Precipitation Method to Enhance Quercetin Dissolution

HPMCAS-HF, HPMCAS-MF and HPMCAS-LF were used as carriers to prepare the amorphous solid dispersions (ASDs) of quercetin (Que) by co-precipitation. The Que ASD based on PVP K30 was prepared by solvent evaporation method. The ability of polymer to inhibit Que crystallization was evaluated. The study f...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of pharmaceutical sciences 2021-09, Vol.110 (9), p.3230-3237
Hauptverfasser:	Wang, Yiru, Fang, Yudan, Zhou, Feng, Liang, Qi, Deng, Yueyi
Format:	Artikel
Sprache:	eng
Schlagworte:	Amorphous solid dispersion Co-precipitation Dissolution HPMCAS Quercetin
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!