Biology and clinical management of hypoplastic MDS: MDS as a bone marrow failure syndrome

Hypoplastic MDS is a subset of MDS characterized by marrow hypocellularity diagnosed in 10–15% of MDS patients. The pathogenesis of this disease shares features of aplastic anemia with activation of the effector T cells against hematopoietic stem and progenitor cells and high-risk MDS with acquisiti...

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Veröffentlicht in:	Best practice & research. Clinical haematology 2021-06, Vol.34 (2), p.101280-101280, Article 101280
Hauptverfasser:	Karantanos, Theodoros, DeZern, Amy E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemia, Aplastic - therapy Biology Bone Marrow Bone marrow failure Bone Marrow Failure Disorders Clinical management Humans Hypoplastic MDS Myelodysplastic Syndromes - therapy
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