Nanomolar Detection of Vitamin C in Artificial Urine using a Glassy Carbon Electrode Modified with Molybdenum Disulfide

Accurate monitoring of vitamins is an indispensable tool in predicting the health condition of humans rapidly. In this work, electrochemical determination of vitamin C was investigated using a glassy carbon electrode modified with molybdenum disulfide (MoS2) transition metal dichalcogenides. To study the electrochemical sensing of MoS2 toward vitamin C, three different synthesis temperatures, 400 degrees, 450 degrees, and 500 degrees C were adopted. MoS2 prepared at 450 degrees C (MS450) exhibited low oxidation potential (0.25 V vs Ag/AgCl) toward electrochemical sensing of vitamin C. The electrochemical sensing behavior was linear in the range of 90 to 590 nM with a sensitivity of 5.83 x 10(-2) mu A mu M-1 and a detection limit of 0.041 mu M. The electrode exhibited anti-interference properties even in artificial urine samples. The results show that MoS2 can be a promising candidate for developing vitamin C electrochemical sensors.