COVID-19 vaccinemRNA-1273 elicits a protective immune profile inmice that is not associated with vaccine-enhanceddiseaseuponSARS-CoV-2 challenge

Vaccine-associated enhanced respiratory disease (VAERD) was previously observed in some preclinical models of severe acute respiratory syndrome (SARS) and MERS coronavirus vaccines. We used the SARS coronavirus 2 (SARS-CoV-2) mouse-adapted, passage 10, lethal challenge virus (MA10) mouse model of ac...

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Veröffentlicht in:	Immunity (Cambridge, Mass.) Mass.), 2021-08, Vol.54 (8), p.1869
Hauptverfasser:	DiPiazza, Anthony T., Leist, Sarah R., Abiona, Olubukola M., Moliva, Juan, Werner, Anne, Minai, Mahnaz, Nagata, Bianca M., Bock, Kevin W., Phung, Emily, Schafer, Alexandra, Dinnon, Kenneth H., Chang, Lauren A., Loomis, Rebecca J., Boyoglu-Barnum, Seyhan, Alvarado, Gabriela S., Sullivan, Nancy J., Edwards, Darin K., Morabito, Kaitlyn M., Mascola, John R., Carfi, Andrea, Corbett, Kizzmekia S., Moore, Ian N., Baric, Ralph S., Graham, Barney S., Ruckwardt, Tracy J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Immunology Life Sciences & Biomedicine Science & Technology
Online-Zugang:	Volltext
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