Adipose Stromal Cell-Secretome Counteracts Profibrotic Signals From IPF Lung Matrices

Introduction: Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease characterized by excess deposition and altered structure of extracellular matrix (ECM) in the lungs. The fibrotic ECM is paramount in directing resident cells toward a profibrotic phenotype. Collagens, an important part of...

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Veröffentlicht in:	Frontiers in pharmacology 2021-07, Vol.12, p.669037-669037, Article 669037
Hauptverfasser:	Vasse, Gwenda F., Van Os, Lisette, De Jager, Marina, Jonker, Marnix R., Borghuis, Theo, Van den Toorn, L. Tim, Jellema, Pytrick, White, Eric S., Van Rijn, Patrick, Harmsen, Martin C., Heijink, Irene H., Melgert, Barbro N., Burgess, Janette K.
Format:	Artikel
Sprache:	eng
Schlagworte:	adipose tissue-derived stromal/stem cells (ASCs) collagen hybridizing peptide decellularized lung matrices denatured collagen extracellular matrix (ECM) idiopathic pulmonary fibrosis (IPF) Life Sciences & Biomedicine Pharmacology Pharmacology & Pharmacy Science & Technology
Online-Zugang:	Volltext
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