Plasminogen deficiency causes reduced angiogenesis and behavioral recovery after stroke in mice

Plasminogen is involved in the process of angiogenesis; however, the underlying mechanism is unclear. Here, we investigated the potential contribution of plasmin/plasminogen in mediating angiogenesis and thereby contributing to functional recovery post-stroke. Wild-type plasminogen naive (Plg+/+) mi...

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Veröffentlicht in:	Journal of cerebral blood flow and metabolism 2021-10, Vol.41 (10), p.2583-2592, Article 0271678
Hauptverfasser:	Fang, Jinghuan, Chopp, Michael, Xin, Hongqi, Zhang, Li, Wang, Fengjie, Golembieski, William, Zhang, Zheng Gang, He, Li, Liu, Zhongwu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Endocrinology & Metabolism Hematology Life Sciences & Biomedicine Male Mice Neovascularization, Pathologic - physiopathology Neurosciences Neurosciences & Neurology Original Plasminogen - deficiency Recovery of Function - physiology Science & Technology Stroke - physiopathology
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