Long‐term impact of coal mine fire smoke on lung mechanics in exposed adults
Background and objective In 2014, a 6‐week‐long fire at the Hazelwood coal mine exposed residents in the adjacent town of Morwell to high concentrations of fine particulate matter with an aerodynamic diameter
Gespeichert in:
| Veröffentlicht in: | Respirology (Carlton, Vic.) Vic.), 2021-09, Vol.26 (9), p.861-868 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 868 |
|---|---|
| container_issue | 9 |
| container_start_page | 861 |
| container_title | Respirology (Carlton, Vic.) |
| container_volume | 26 |
| creator | Holt, Nicolette R. Gao, Caroline X. Borg, Brigitte M. Brown, David Broder, Jonathan C. Ikin, Jillian Makar, Annie McCrabb, Thomas Nilsen, Kris Thompson, Bruce R. Abramson, Michael J. |
| description | Background and objective
In 2014, a 6‐week‐long fire at the Hazelwood coal mine exposed residents in the adjacent town of Morwell to high concentrations of fine particulate matter with an aerodynamic diameter |
| doi_str_mv | 10.1111/resp.14102 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2562044718</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2562044718</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3702-b667b0fcccf9619428f26aafc4f0532cfbc901adcdfda4b874e78d86b3beeb083</originalsourceid><addsrcrecordid>eNp9kMtOwzAQRS0EEqWw4QsssUNK8SuvJapKQaoA8VhbjjMuLkkc7ETQHZ_AN_IlpIQ1s5lZnLlXOgidUjKjw1x4CO2MCkrYHppQIUhEM8H3h5szHqVpnh-ioxA2hBAek3iCbleuWX9_fnXga2zrVukOO4O1UxWubQPYWA841O4VsGtw1TdrXIN-UY3VAdsGw0frApRYlX3VhWN0YFQV4ORvT9Hz1eJpfh2t7pY388tVpHlKWFQkSVoQo7U2eUJzwTLDEqWMFobEnGlT6JxQVerSlEoUWSogzcosKXgBUJCMT9HZmNt699ZD6OTG9b4ZKiWLE0aESOmOOh8p7V0IHoxsva2V30pK5M6X3PmSv74GmI7wu61g-w8pHxaP9-PPD75mbyQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2562044718</pqid></control><display><type>article</type><title>Long‐term impact of coal mine fire smoke on lung mechanics in exposed adults</title><source>Wiley-Blackwell subscription journals</source><creator>Holt, Nicolette R. ; Gao, Caroline X. ; Borg, Brigitte M. ; Brown, David ; Broder, Jonathan C. ; Ikin, Jillian ; Makar, Annie ; McCrabb, Thomas ; Nilsen, Kris ; Thompson, Bruce R. ; Abramson, Michael J.</creator><creatorcontrib>Holt, Nicolette R. ; Gao, Caroline X. ; Borg, Brigitte M. ; Brown, David ; Broder, Jonathan C. ; Ikin, Jillian ; Makar, Annie ; McCrabb, Thomas ; Nilsen, Kris ; Thompson, Bruce R. ; Abramson, Michael J.</creatorcontrib><description>Background and objective
In 2014, a 6‐week‐long fire at the Hazelwood coal mine exposed residents in the adjacent town of Morwell to high concentrations of fine particulate matter with an aerodynamic diameter < 2.5 μm (PM2.5). The long‐term health consequences are being evaluated as part of the Hazelwood Health Study.
Methods
Approximately 3.5–4 years after the mine fire, adults from Morwell (n = 346) and the comparison town Sale (n = 173) participated in the longitudinal Respiratory Stream of the Study. Individual PM2.5 exposure was retrospectively modelled. Lung mechanics were assessed using the forced oscillation technique (FOT), utilizing pressure waves to measure respiratory system resistance (Rrs) and reactance (Xrs). Multivariate linear regression was used to evaluate associations between PM2.5 and transformed Rrs at 5 Hz, area under the reactance curve (AX5) and Xrs at 5 Hz controlling for key confounders.
Results
There were clear dose–response relationships between increasing mine fire PM2.5 and worsening lung mechanics, including a reduction in post‐bronchodilator (BD) Xrs5 and an increase in AX5. A 10 μg/m3 increase in mine fire‐related PM2.5 was associated with a 0.015 (95% CI: 0.004, 0.027) reduction in exponential (Xrs5) post‐BD, which was comparable to 4.7 years of ageing. Similarly, the effect of exposure was associated with a 0.072 (0.005, 0.138) increase in natural log (lnAX5) post‐BD, equivalent to 3.9 years of ageing.
Conclusion
This is the first study using FOT in adults evaluating long‐term respiratory outcomes after medium‐term ambient PM2.5 exposure to coal mine fire smoke. These results should inform public health policies and planning for future events.
Four years after a mine fire of 6 weeks duration, each 10 μg/m3 increase in particulate matter with an aerodynamic diameter < 2.5 μm (PM2.5) exposure was associated with negative respiratory system reactance equivalent to 4.7 years of ageing, and an increase in the area under the reactance curve equivalent to 3.9 years of ageing, in exposed adults.
See related Editorial</description><identifier>ISSN: 1323-7799</identifier><identifier>EISSN: 1440-1843</identifier><identifier>DOI: 10.1111/resp.14102</identifier><language>eng</language><publisher>Chichester, UK: John Wiley & Sons, Ltd</publisher><subject>Aging ; air pollution ; Coal ; coal mine fire ; Coal mining ; environmental lung disease ; forced oscillation technique ; lung mechanics ; Mechanics ; Particulate matter ; Public health ; respiratory ; Respiratory diseases ; Respiratory system ; Smoke</subject><ispartof>Respirology (Carlton, Vic.), 2021-09, Vol.26 (9), p.861-868</ispartof><rights>2021 Asian Pacific Society of Respirology.</rights><rights>2021 Asian Pacific Society of Respirology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3702-b667b0fcccf9619428f26aafc4f0532cfbc901adcdfda4b874e78d86b3beeb083</citedby><cites>FETCH-LOGICAL-c3702-b667b0fcccf9619428f26aafc4f0532cfbc901adcdfda4b874e78d86b3beeb083</cites><orcidid>0000-0003-2122-8381 ; 0000-0002-9954-0538 ; 0000-0003-0794-0129 ; 0000-0002-5885-0652</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fresp.14102$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fresp.14102$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,781,785,1418,27926,27927,45576,45577</link.rule.ids></links><search><creatorcontrib>Holt, Nicolette R.</creatorcontrib><creatorcontrib>Gao, Caroline X.</creatorcontrib><creatorcontrib>Borg, Brigitte M.</creatorcontrib><creatorcontrib>Brown, David</creatorcontrib><creatorcontrib>Broder, Jonathan C.</creatorcontrib><creatorcontrib>Ikin, Jillian</creatorcontrib><creatorcontrib>Makar, Annie</creatorcontrib><creatorcontrib>McCrabb, Thomas</creatorcontrib><creatorcontrib>Nilsen, Kris</creatorcontrib><creatorcontrib>Thompson, Bruce R.</creatorcontrib><creatorcontrib>Abramson, Michael J.</creatorcontrib><title>Long‐term impact of coal mine fire smoke on lung mechanics in exposed adults</title><title>Respirology (Carlton, Vic.)</title><description>Background and objective
In 2014, a 6‐week‐long fire at the Hazelwood coal mine exposed residents in the adjacent town of Morwell to high concentrations of fine particulate matter with an aerodynamic diameter < 2.5 μm (PM2.5). The long‐term health consequences are being evaluated as part of the Hazelwood Health Study.
Methods
Approximately 3.5–4 years after the mine fire, adults from Morwell (n = 346) and the comparison town Sale (n = 173) participated in the longitudinal Respiratory Stream of the Study. Individual PM2.5 exposure was retrospectively modelled. Lung mechanics were assessed using the forced oscillation technique (FOT), utilizing pressure waves to measure respiratory system resistance (Rrs) and reactance (Xrs). Multivariate linear regression was used to evaluate associations between PM2.5 and transformed Rrs at 5 Hz, area under the reactance curve (AX5) and Xrs at 5 Hz controlling for key confounders.
Results
There were clear dose–response relationships between increasing mine fire PM2.5 and worsening lung mechanics, including a reduction in post‐bronchodilator (BD) Xrs5 and an increase in AX5. A 10 μg/m3 increase in mine fire‐related PM2.5 was associated with a 0.015 (95% CI: 0.004, 0.027) reduction in exponential (Xrs5) post‐BD, which was comparable to 4.7 years of ageing. Similarly, the effect of exposure was associated with a 0.072 (0.005, 0.138) increase in natural log (lnAX5) post‐BD, equivalent to 3.9 years of ageing.
Conclusion
This is the first study using FOT in adults evaluating long‐term respiratory outcomes after medium‐term ambient PM2.5 exposure to coal mine fire smoke. These results should inform public health policies and planning for future events.
Four years after a mine fire of 6 weeks duration, each 10 μg/m3 increase in particulate matter with an aerodynamic diameter < 2.5 μm (PM2.5) exposure was associated with negative respiratory system reactance equivalent to 4.7 years of ageing, and an increase in the area under the reactance curve equivalent to 3.9 years of ageing, in exposed adults.
See related Editorial</description><subject>Aging</subject><subject>air pollution</subject><subject>Coal</subject><subject>coal mine fire</subject><subject>Coal mining</subject><subject>environmental lung disease</subject><subject>forced oscillation technique</subject><subject>lung mechanics</subject><subject>Mechanics</subject><subject>Particulate matter</subject><subject>Public health</subject><subject>respiratory</subject><subject>Respiratory diseases</subject><subject>Respiratory system</subject><subject>Smoke</subject><issn>1323-7799</issn><issn>1440-1843</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kMtOwzAQRS0EEqWw4QsssUNK8SuvJapKQaoA8VhbjjMuLkkc7ETQHZ_AN_IlpIQ1s5lZnLlXOgidUjKjw1x4CO2MCkrYHppQIUhEM8H3h5szHqVpnh-ioxA2hBAek3iCbleuWX9_fnXga2zrVukOO4O1UxWubQPYWA841O4VsGtw1TdrXIN-UY3VAdsGw0frApRYlX3VhWN0YFQV4ORvT9Hz1eJpfh2t7pY388tVpHlKWFQkSVoQo7U2eUJzwTLDEqWMFobEnGlT6JxQVerSlEoUWSogzcosKXgBUJCMT9HZmNt699ZD6OTG9b4ZKiWLE0aESOmOOh8p7V0IHoxsva2V30pK5M6X3PmSv74GmI7wu61g-w8pHxaP9-PPD75mbyQ</recordid><startdate>202109</startdate><enddate>202109</enddate><creator>Holt, Nicolette R.</creator><creator>Gao, Caroline X.</creator><creator>Borg, Brigitte M.</creator><creator>Brown, David</creator><creator>Broder, Jonathan C.</creator><creator>Ikin, Jillian</creator><creator>Makar, Annie</creator><creator>McCrabb, Thomas</creator><creator>Nilsen, Kris</creator><creator>Thompson, Bruce R.</creator><creator>Abramson, Michael J.</creator><general>John Wiley & Sons, Ltd</general><general>Wiley Subscription Services, Inc</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><orcidid>https://orcid.org/0000-0003-2122-8381</orcidid><orcidid>https://orcid.org/0000-0002-9954-0538</orcidid><orcidid>https://orcid.org/0000-0003-0794-0129</orcidid><orcidid>https://orcid.org/0000-0002-5885-0652</orcidid></search><sort><creationdate>202109</creationdate><title>Long‐term impact of coal mine fire smoke on lung mechanics in exposed adults</title><author>Holt, Nicolette R. ; Gao, Caroline X. ; Borg, Brigitte M. ; Brown, David ; Broder, Jonathan C. ; Ikin, Jillian ; Makar, Annie ; McCrabb, Thomas ; Nilsen, Kris ; Thompson, Bruce R. ; Abramson, Michael J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3702-b667b0fcccf9619428f26aafc4f0532cfbc901adcdfda4b874e78d86b3beeb083</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Aging</topic><topic>air pollution</topic><topic>Coal</topic><topic>coal mine fire</topic><topic>Coal mining</topic><topic>environmental lung disease</topic><topic>forced oscillation technique</topic><topic>lung mechanics</topic><topic>Mechanics</topic><topic>Particulate matter</topic><topic>Public health</topic><topic>respiratory</topic><topic>Respiratory diseases</topic><topic>Respiratory system</topic><topic>Smoke</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Holt, Nicolette R.</creatorcontrib><creatorcontrib>Gao, Caroline X.</creatorcontrib><creatorcontrib>Borg, Brigitte M.</creatorcontrib><creatorcontrib>Brown, David</creatorcontrib><creatorcontrib>Broder, Jonathan C.</creatorcontrib><creatorcontrib>Ikin, Jillian</creatorcontrib><creatorcontrib>Makar, Annie</creatorcontrib><creatorcontrib>McCrabb, Thomas</creatorcontrib><creatorcontrib>Nilsen, Kris</creatorcontrib><creatorcontrib>Thompson, Bruce R.</creatorcontrib><creatorcontrib>Abramson, Michael J.</creatorcontrib><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>Respirology (Carlton, Vic.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Holt, Nicolette R.</au><au>Gao, Caroline X.</au><au>Borg, Brigitte M.</au><au>Brown, David</au><au>Broder, Jonathan C.</au><au>Ikin, Jillian</au><au>Makar, Annie</au><au>McCrabb, Thomas</au><au>Nilsen, Kris</au><au>Thompson, Bruce R.</au><au>Abramson, Michael J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long‐term impact of coal mine fire smoke on lung mechanics in exposed adults</atitle><jtitle>Respirology (Carlton, Vic.)</jtitle><date>2021-09</date><risdate>2021</risdate><volume>26</volume><issue>9</issue><spage>861</spage><epage>868</epage><pages>861-868</pages><issn>1323-7799</issn><eissn>1440-1843</eissn><abstract>Background and objective
In 2014, a 6‐week‐long fire at the Hazelwood coal mine exposed residents in the adjacent town of Morwell to high concentrations of fine particulate matter with an aerodynamic diameter < 2.5 μm (PM2.5). The long‐term health consequences are being evaluated as part of the Hazelwood Health Study.
Methods
Approximately 3.5–4 years after the mine fire, adults from Morwell (n = 346) and the comparison town Sale (n = 173) participated in the longitudinal Respiratory Stream of the Study. Individual PM2.5 exposure was retrospectively modelled. Lung mechanics were assessed using the forced oscillation technique (FOT), utilizing pressure waves to measure respiratory system resistance (Rrs) and reactance (Xrs). Multivariate linear regression was used to evaluate associations between PM2.5 and transformed Rrs at 5 Hz, area under the reactance curve (AX5) and Xrs at 5 Hz controlling for key confounders.
Results
There were clear dose–response relationships between increasing mine fire PM2.5 and worsening lung mechanics, including a reduction in post‐bronchodilator (BD) Xrs5 and an increase in AX5. A 10 μg/m3 increase in mine fire‐related PM2.5 was associated with a 0.015 (95% CI: 0.004, 0.027) reduction in exponential (Xrs5) post‐BD, which was comparable to 4.7 years of ageing. Similarly, the effect of exposure was associated with a 0.072 (0.005, 0.138) increase in natural log (lnAX5) post‐BD, equivalent to 3.9 years of ageing.
Conclusion
This is the first study using FOT in adults evaluating long‐term respiratory outcomes after medium‐term ambient PM2.5 exposure to coal mine fire smoke. These results should inform public health policies and planning for future events.
Four years after a mine fire of 6 weeks duration, each 10 μg/m3 increase in particulate matter with an aerodynamic diameter < 2.5 μm (PM2.5) exposure was associated with negative respiratory system reactance equivalent to 4.7 years of ageing, and an increase in the area under the reactance curve equivalent to 3.9 years of ageing, in exposed adults.
See related Editorial</abstract><cop>Chichester, UK</cop><pub>John Wiley & Sons, Ltd</pub><doi>10.1111/resp.14102</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-2122-8381</orcidid><orcidid>https://orcid.org/0000-0002-9954-0538</orcidid><orcidid>https://orcid.org/0000-0003-0794-0129</orcidid><orcidid>https://orcid.org/0000-0002-5885-0652</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1323-7799 |
| ispartof | Respirology (Carlton, Vic.), 2021-09, Vol.26 (9), p.861-868 |
| issn | 1323-7799 1440-1843 |
| language | eng |
| recordid | cdi_proquest_journals_2562044718 |
| source | Wiley-Blackwell subscription journals |
| subjects | Aging air pollution Coal coal mine fire Coal mining environmental lung disease forced oscillation technique lung mechanics Mechanics Particulate matter Public health respiratory Respiratory diseases Respiratory system Smoke |
| title | Long‐term impact of coal mine fire smoke on lung mechanics in exposed adults |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-17T17%3A49%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Long%E2%80%90term%20impact%20of%20coal%20mine%20fire%20smoke%20on%20lung%20mechanics%20in%20exposed%20adults&rft.jtitle=Respirology%20(Carlton,%20Vic.)&rft.au=Holt,%20Nicolette%20R.&rft.date=2021-09&rft.volume=26&rft.issue=9&rft.spage=861&rft.epage=868&rft.pages=861-868&rft.issn=1323-7799&rft.eissn=1440-1843&rft_id=info:doi/10.1111/resp.14102&rft_dat=%3Cproquest_cross%3E2562044718%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2562044718&rft_id=info:pmid/&rfr_iscdi=true |