Kaolin-catalysed one-pot synthesis of thiophene containing aminonaphthols under solvent-free condition and their in vitro anticancer and antioxidant activity

An efficient and eco-friendly synthetic protocol via a one-pot three-component reaction to yield thiophene containing aminonaphthols (Betti bases) is reported. Kaolin was used as a heterogeneous catalyst and a series of Betti bases were synthesized under solvent-free condition. The synthesized deriv...

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