LightBBB: computational prediction model of blood–brain-barrier penetration based on LightGBM

Abstract Motivation Identification of blood–brain barrier (BBB) permeability of a compound is a major challenge in neurotherapeutic drug discovery. Conventional approaches for BBB permeability measurement are expensive, time-consuming and labor-intensive. BBB permeability is associated with diverse...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	BIOINFORMATICS 2021-05, Vol.37 (8), p.1135-1139
Hauptverfasser:	Shaker, Bilal, Yu, Myeong-Sang, Song, Jin Sook, Ahn, Sunjoo, Ryu, Jae Yong, Oh, Kwang-Seok, Na, Dokyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemical Research Methods Biochemistry & Molecular Biology Biotechnology & Applied Microbiology Computer Science Computer Science, Interdisciplinary Applications Life Sciences & Biomedicine Mathematical & Computational Biology Mathematics Physical Sciences Science & Technology Statistics & Probability Technology
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!