Neurally adjusted ventilatory assist in neonates with congenital diaphragmatic hernia

Objective To measure short-term outcomes of neonates with congenital diaphragmatic hernia (CDH) while on Neurally Adjusted Ventilator Assist (NAVA), and to measure the impact of a congenitally abnormal diaphragm on NAVA ventilator indices. Study design First, we conducted a retrospective-cohort anal...

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Veröffentlicht in:Journal of perinatology 2021-08, Vol.41 (8), p.1910-1915
Hauptverfasser: Kurland, Yonatan, Gurung, Kamal, Pallotto, Eugenia K., Manimtim, Winston, Feldman, Keith, Staggs, Vincent S., Truog, William
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Sprache:eng
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Zusammenfassung:Objective To measure short-term outcomes of neonates with congenital diaphragmatic hernia (CDH) while on Neurally Adjusted Ventilator Assist (NAVA), and to measure the impact of a congenitally abnormal diaphragm on NAVA ventilator indices. Study design First, we conducted a retrospective-cohort analysis of 16 neonates with CDH placed on NAVA over a treatment period of 72 h. Second, we performed a case–control study comparing NAVA level and Edi between neonates with CDH and those without CDH. Results Compared to pre-NAVA, there were clinically meaningful improvements in PIP ( p  
ISSN:0743-8346
1476-5543
DOI:10.1038/s41372-021-01098-3