Functionalized 5‐Amino‐4‐cyanoxazoles, their Hetero‐ and Macrocyclic Derivatives: Preparation and Synthetic Applications

An approach to a series of new 5‐amino‐4‐cyanoxazoles is described. Synthesis of the title compounds relied on a two‐step sequence including heterocyclization of 2‐amido‐3,3‐dichloroacrylonitriles with aliphatic secondary amines (dimethylamine, morpholine), primary aliphatic amines with active funct...

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Veröffentlicht in:	European journal of organic chemistry 2021-12, Vol.2021 (47), p.6511-6523
Hauptverfasser:	Merzhyievskyi, Danylo O., Shablykin, Oleh V., Shablykina, Olga V., Kozytskiy, Andriy V., Rusanov, Eduard B., Moskvina, Viktoriia S., Brovarets, Volodymyr S.
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Amino-3,3-dichloroacrylonitrile Aliphatic amines Amino acids Aniline Ethyl esters Functional groups Glycine Heterocyclization Macrocycles Morpholine Oxazole Oxazole synthesis Recyclization
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