In vitro degradation assessment of calcium fluoride-doped hydroxyapatite coating prepared by pulsed laser deposition

In vitro degradation assessment of calcium fluoride-doped hydroxyapatite coating prepared by pulsed laser deposition

The surface properties of bone tissue engineered scaffolds are essential for cell attachment, proliferation, and differentiation. Calcium fluoride-doped hydroxyapatite (F-HA) coating prepared by pulsed laser deposition can rapidly form a nanopore structure through ion exchange in the simulated body...

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Veröffentlicht in:Surface & coatings technology 2021-06, Vol.416, p.127177, Article 127177
Hauptverfasser: Cao, Jinxing, Lian, Ruizhe, Jiang, Xiaohong, Rogachev, Aleksandr V.
Format: Artikel
Sprache:eng
Schlagworte:
Apatite
Biomedical materials
Body fluids
Bones
Calcium fluoride
Cell proliferation
Corrosion resistance
Degradation
Fluorides
Hydroxyapatite
In vitro methods and tests
Ion exchange
Nanopore
Protective coatings
Pulsed laser deposition
Pulsed lasers
Scaffolds
Surface properties
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Zusammenfassung:The surface properties of bone tissue engineered scaffolds are essential for cell attachment, proliferation, and differentiation. Calcium fluoride-doped hydroxyapatite (F-HA) coating prepared by pulsed laser deposition can rapidly form a nanopore structure through ion exchange in the simulated body fluid. Results showed that F-HA coating can accelerate the apatite-like deposition and improve the corrosion resistance of the coating. Results also revealed that F-HA coating can promote cell proliferation (p 
ISSN:0257-8972
1879-3347
DOI:10.1016/j.surfcoat.2021.127177