Design and characterization of high-affinity synthetic peptides as bioreceptors for diagnosis of cutaneous leishmaniasis

Cutaneous leishmaniasis (CL) is one of the illnesses caused by Leishmania parasite infection, which can be asymptomatic or severe according to the infecting Leishmania strain. CL is commonly diagnosed by directly detecting the parasites or their DNA in tissue samples. New diagnostic methodologies ta...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2021-07, Vol.413 (17), p.4545-4555
Hauptverfasser:	Prada, Y. Andrea, Soler, Maria, Guzmán, Fanny, Castillo, John J., Lechuga, Laura M., Mejía-Ospino, Enrique
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid phosphatase Acid Phosphatase - analysis Affinity Analysis Analytical Chemistry Antibodies Binding Sites Biochemical Research Methods Biochemistry Biochemistry & Molecular Biology Biomarkers Biosensors Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Chemistry, Analytical Cutaneous leishmaniasis Food Science Glycoproteins Humans Identification and classification In vivo methods and tests Infections Laboratory Medicine Leishmania Leishmania - enzymology Leishmania - isolation & purification Leishmaniasis, Cutaneous - diagnosis Leishmaniasis, Cutaneous - parasitology Life Sciences & Biomedicine Membrane Proteins - analysis Methods Models, Molecular Molecular weight Monitoring/Environmental Analysis Parasites Parasitic diseases Peptides Peptides - chemical synthesis Peptides - chemistry Peptidomimetics Peptidomimetics - chemical synthesis Peptidomimetics - chemistry Physical Sciences Properties Proteins Proteoglycans - analysis Protozoan Proteins - analysis Research Paper Science & Technology Structure Surface plasmon resonance Surface Plasmon Resonance - methods Synthetic peptides Vector-borne diseases
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